| Compound ID |
Compound Name |
Compound Formula |
|
CP0324876
|
3-chloro-N-[2,4-difluoro-3-[4-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)triazol-1-yl]phenyl]benzenesulfonamide
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|
C21H14ClF2N7O3S
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
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CP0575966
|
3-bromo-N-[2,4-difluoro-3-[4-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)triazol-1-yl]phenyl]benzenesulfonamide
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|
C21H14BrF2N7O3S
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
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CP0327249
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N-[2,4-difluoro-3-[4-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)triazol-1-yl]phenyl]-3-methoxybenzenesulfonamide
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|
C22H17F2N7O4S
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
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CP0366487
|
3-chloro-N-[2-fluoro-3-[4-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)triazol-1-yl]phenyl]benzenesulfonamide
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|
C21H15ClFN7O3S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
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CP0389189
|
3-cyano-N-[2,4-difluoro-3-[2-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]benzenesulfonamide
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|
C22H13F2N5O3S
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
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CP0350484
|
3-cyano-N-[2,4-difluoro-3-[4-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)triazol-1-yl]phenyl]benzenesulfonamide
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|
C22H14F2N8O3S
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
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CP0537975
|
N-[2,4-difluoro-3-[4-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)triazol-1-yl]phenyl]benzenesulfonamide
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|
C21H15F2N7O3S
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
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CP0327247
|
N-[2,4-difluoro-3-[4-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)triazol-1-yl]phenyl]-3-phenylbenzenesulfonamide
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|
C27H19F2N7O3S
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
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CP0366489
|
3-chloro-N-[2,4-difluoro-3-[2-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]benzenesulfonamide
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|
C21H13ClF2N4O3S
|
2
|
| 1 |
IC50 = 4.2 nM
|
|
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| 2 |
IC50 = 14.7 nM
|
|
|
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CP0577023
|
N-[2,4-difluoro-3-[4-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)triazol-1-yl]phenyl]naphthalene-1-sulfonamide
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|
C25H17F2N7O3S
|
1
|
| 1 |
IC50 = 4.2 nM
|
|
|
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CP0562348
|
N-[2,4-difluoro-3-[4-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)triazol-1-yl]phenyl]-3-methylbenzenesulfonamide
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|
C22H17F2N7O3S
|
1
|
| 1 |
IC50 = 4.4 nM
|
|
|
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CP0574924
|
N-[2,4-difluoro-3-[4-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)triazol-1-yl]phenyl]naphthalene-2-sulfonamide
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|
C25H17F2N7O3S
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
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CP0468877
|
3-bromo-N-[2,4-difluoro-3-[2-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]benzenesulfonamide
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|
C21H13BrF2N4O3S
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
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CP0417520
|
2-chloro-N-[2,4-difluoro-3-[2-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]benzenesulfonamide
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|
C21H13ClF2N4O3S
|
1
|
| 1 |
IC50 = 5.1 nM
|
|
|
|
CP0553717
|
3-chloro-N-[2,4-difluoro-3-[2-(1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]benzenesulfonamide
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|
C20H11ClF2N4O2S
|
1
|
| 1 |
IC50 = 5.1 nM
|
|
|
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CP0561871
|
3-chloro-N-[4-fluoro-3-[4-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)triazol-1-yl]phenyl]benzenesulfonamide
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|
C21H15ClFN7O3S
|
1
|
| 1 |
IC50 = 5.7 nM
|
|
|
|
CP0356023
|
N-[2,4-difluoro-3-[4-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)triazol-1-yl]phenyl]-3-propan-2-ylbenzenesulfonamide
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|
C24H21F2N7O3S
|
1
|
| 1 |
IC50 = 6.9 nM
|
|
|
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CP0417522
|
N-[2,4-difluoro-3-[2-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]-3-methoxybenzenesulfonamide
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|
C22H16F2N4O4S
|
1
|
| 1 |
IC50 = 7.5 nM
|
|
|
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CP0366488
|
N-[3-[4-(2-aminopyrimidin-5-yl)triazol-1-yl]-2,4-difluorophenyl]-3-chlorobenzenesulfonamide
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|
C18H12ClF2N7O2S
|
1
|
| 1 |
IC50 = 8.9 nM
|
|
|
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CP0455643
|
2,3-dichloro-N-[2,4-difluoro-3-[2-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]benzenesulfonamide
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|
C21H12Cl2F2N4O3S
|
1
|
| 1 |
IC50 = 9.6 nM
|
|
|
|
CP0541500
|
N-[2,4-difluoro-3-[2-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]-3-methylbenzenesulfonamide
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|
C22H16F2N4O3S
|
1
|
| 1 |
IC50 = 12.1 nM
|
|
|
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CP0560059
|
4-chloro-N-[2,4-difluoro-3-[2-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]benzenesulfonamide
Show/Hide
|
C21H13ClF2N4O3S
|
1
|
| 1 |
IC50 = 16.8 nM
|
|
|
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CP0432644
|
N-[2,4-difluoro-3-[2-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]benzenesulfonamide
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|
C21H14F2N4O3S
|
1
|
| 1 |
IC50 = 19.2 nM
|
|
|
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CP0548922
|
3-chloro-N-[2,4-difluoro-3-[2-(1H-pyrrolo[2,3-b]pyridin-5-yl)ethynyl]phenyl]benzenesulfonamide
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|
C21H12ClF2N3O2S
|
1
|
| 1 |
IC50 = 22.6 nM
|
|
|
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CP0006321
|
PLX-4032
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|
C23H18ClF2N3O3S
|
2
|
| 1 |
IC50 = 23 nM
|
|
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| 2 |
IC50 = 31.4 nM
|
|
|
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CP0211350
|
3-chloro-N-[3-[4-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)triazol-1-yl]phenyl]benzenesulfonamide
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|
C21H16ClN7O3S
|
1
|
| 1 |
IC50 = 24.7 nM
|
|
|
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CP0324877
|
3-chloro-N-[2,4-difluoro-3-[5-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)-1,2,4-oxadiazol-3-yl]phenyl]benzenesulfonamide
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|
C21H13ClF2N6O4S
|
1
|
| 1 |
IC50 = 29 nM
|
|
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CP0566163
|
3-chloro-N-[2,4-difluoro-3-[2-(3-propan-2-yloxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]benzenesulfonamide
Show/Hide
|
C23H17ClF2N4O3S
|
1
|
| 1 |
IC50 = 42.7 nM
|
|
|
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CP0350485
|
N-[3-[4-(6-aminopyridin-3-yl)triazol-1-yl]-2,4-difluorophenyl]-3-chlorobenzenesulfonamide
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|
C19H13ClF2N6O2S
|
1
|
| 1 |
IC50 = 46.2 nM
|
|
|
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CP0362965
|
1-(3-chlorophenyl)-3-[2,4-difluoro-3-[4-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)triazol-1-yl]phenyl]urea
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|
C22H15ClF2N8O2
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
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CP0561870
|
3-chloro-N-[2,4-difluoro-3-[4-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)triazol-1-yl]phenyl]benzamide
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|
C22H14ClF2N7O2
|
1
|
| 1 |
IC50 = 54.3 nM
|
|
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CP0562349
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3-chloro-N-[2,4-difluoro-3-[5-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)-1,3,4-oxadiazol-2-yl]phenyl]benzenesulfonamide
Show/Hide
|
C21H13ClF2N6O4S
|
1
|
| 1 |
IC50 = 63.3 nM
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CP0537977
|
2-(3-chlorophenyl)-N-[2,4-difluoro-3-[4-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)triazol-1-yl]phenyl]acetamide
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|
C23H16ClF2N7O2
|
1
|
| 1 |
IC50 = 85.7 nM
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CP0470877
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3-chloro-N-[3-[2-(3-cyclopentyloxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]-2,4-difluorophenyl]benzenesulfonamide
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|
C25H19ClF2N4O3S
|
1
|
| 1 |
IC50 = 143.7 nM
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CP0324874
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3-chloro-N-[2,4-dichloro-3-[4-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)triazol-1-yl]phenyl]benzenesulfonamide
Show/Hide
|
C21H14Cl3N7O3S
|
1
|
| 1 |
IC50 = 413.3 nM
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CP0462335
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3-chloro-N-[2,4-difluoro-3-[2-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)-1H-imidazol-5-yl]phenyl]benzenesulfonamide
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|
C22H15ClF2N6O3S
|
1
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| 1 |
IC50 = 983 nM
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CP0541501
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3-chloro-N-[2,4-difluoro-3-[2-(1H-indazol-5-yl)ethynyl]phenyl]benzenesulfonamide
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|
C21H12ClF2N3O2S
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1
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| 1 |
IC50 = 994.1 nM
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CP0491727
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3-chloro-N-[2,4-difluoro-3-[2-(1-methylpyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]benzenesulfonamide
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|
C21H13ClF2N4O2S
|
1
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| 1 |
IC50 > 30000 nM
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