Brief Information of the Compound and Protein
Compound Name
PLX-4032
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PubChem ID
CID: 42611257
SID: 123055406
Canonical SMILES
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(cc23)-c2ccc(Cl)cc2)c1F
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Compound Formula C23H18ClF2N3O3S
Compound Structure
Protein Name
Mitogen-activated protein kinase kinase kinase 20
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase MLK family
>
TKL protein kinase MLK subfamily
Uniprot ID
Q9NYL2
Gene Name
MAP3K20
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 23 nM
   TI
   LI
   LO
   TS
2
IC50 = 31.4 nM
   TI
   LI
   LO
   TS