| Compound ID |
Compound Name |
Compound Formula |
|
CP0666580
|
Dimethyl-(tetrahydro-pyran-4-yl)-{4-[(3-p-tolyl-8,9-dihydro-7H-benzocycloheptene-6-carbonyl)-amino]-benzyl}-ammonium chloride(TAK-779)
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|
C33H39ClN2O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
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CP0396523
|
N-[1-[3-[1-(3,4-dichloroanilino)-5-oxo-8,9-dihydro-7H-pyrido[4,3-c]azepin-6-yl]propyl]piperidin-4-yl]-N-methylmethanesulfonamide
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|
C25H33Cl2N5O3S
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
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CP0546763
|
N-[1-[3-[1-(4-chloroanilino)-5-oxo-8,9-dihydro-7H-pyrido[4,3-c]azepin-6-yl]propyl]piperidin-4-yl]-N-methylmethanesulfonamide
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|
C25H34ClN5O3S
|
1
|
| 1 |
IC50 = 74 nM
|
|
|
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CP0546765
|
1-(3,4-dichloroanilino)-6-[3-(4-phenylpiperidin-1-yl)propyl]-8,9-dihydro-7H-pyrido[4,3-c]azepin-5-one
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|
C29H32Cl2N4O
|
1
|
| 1 |
IC50 = 195 nM
|
|
|
|
CP0566425
|
N-[1-[3-[1-(3,4-dichloroanilino)-5-oxo-8,9-dihydro-7H-pyrido[4,3-c]azepin-6-yl]propyl]piperidin-4-yl]methanesulfonamide
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|
C24H31Cl2N5O3S
|
1
|
| 1 |
IC50 = 336 nM
|
|
|
|
CP0519958
|
N-[1-[3-[1-(3,4-dichloroanilino)-5-oxo-8,9-dihydro-7H-pyrido[4,3-c]azepin-6-yl]propyl]piperidin-4-yl]-N-methylethanesulfonamide
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|
C26H35Cl2N5O3S
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0456371
|
N-methyl-N-[1-[3-[5-oxo-1-(pyridin-2-ylamino)-8,9-dihydro-7H-pyrido[4,3-c]azepin-6-yl]propyl]piperidin-4-yl]methanesulfonamide
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|
C24H34N6O3S
|
1
|
| 1 |
IC50 = 550 nM
|
|
|
|
CP0485564
|
N-[1-[3-[5-(3,4-dichloroanilino)-1-oxo-3,4-dihydro-2,6-naphthyridin-2-yl]propyl]piperidin-4-yl]-N-methylmethanesulfonamide
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|
C24H31Cl2N5O3S
|
1
|
| 1 |
IC50 = 638 nM
|
|
|
|
CP0389882
|
1-(3,4-dichloroanilino)-6-(3-spiro[indene-1,4'-piperidine]-1'-ylpropyl)-8,9-dihydro-7H-pyrido[4,3-c]azepin-5-one
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|
C31H32Cl2N4O
|
1
|
| 1 |
IC50 = 720 nM
|
|
|
|
CP0556230
|
1-(3,4-dichloroanilino)-6-(3-piperidin-1-ylpropyl)-8,9-dihydro-7H-pyrido[4,3-c]azepin-5-one
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|
C23H28Cl2N4O
|
1
|
| 1 |
IC50 = 1261 nM
|
|
|
|
CP0485567
|
1-(3,4-dichloroanilino)-6-[3-(4-methoxypiperidin-1-yl)propyl]-8,9-dihydro-7H-pyrido[4,3-c]azepin-5-one
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|
C24H30Cl2N4O2
|
1
|
| 1 |
IC50 = 1566 nM
|
|
|
|
CP0396521
|
1-(3,4-dichloroanilino)-6-(3-spiro[1H-2-benzothiophene-3,4'-piperidine]-1'-ylpropyl)-8,9-dihydro-7H-pyrido[4,3-c]azepin-5-one
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|
C30H32Cl2N4OS
|
1
|
| 1 |
IC50 = 1614 nM
|
|
|
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CP0546764
|
N-[1-[3-[1-(4-chloro-3-fluoroanilino)-5-oxo-8,9-dihydro-7H-pyrido[4,3-c]azepin-6-yl]propyl]piperidin-4-yl]-N-methylmethanesulfonamide
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|
C25H33ClFN5O3S
|
1
|
| 1 |
IC50 = 1731 nM
|
|
|
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CP0566424
|
N-methyl-N-[1-[3-[5-oxo-1-[3-(trifluoromethyl)anilino]-8,9-dihydro-7H-pyrido[4,3-c]azepin-6-yl]propyl]piperidin-4-yl]methanesulfonamide
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|
C26H34F3N5O3S
|
1
|
| 1 |
IC50 = 1821 nM
|
|
|
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CP0389881
|
N-[1-[3-[1-(3,4-dichlorophenoxy)-5-oxo-8,9-dihydro-7H-pyrido[4,3-c]azepin-6-yl]propyl]piperidin-4-yl]-N-methylmethanesulfonamide
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|
C25H32Cl2N4O4S
|
1
|
| 1 |
IC50 = 2466 nM
|
|
|
|
CP0563232
|
N-[1-[3-[7-(3,4-dichloroanilino)-1-oxo-3,4-dihydro-2,6-naphthyridin-2-yl]propyl]piperidin-4-yl]-N-methylmethanesulfonamide
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|
C24H31Cl2N5O3S
|
1
|
| 1 |
IC50 = 2502 nM
|
|
|
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CP0426432
|
N-[1-[3-[1-(3,5-dichloroanilino)-5-oxo-8,9-dihydro-7H-pyrido[4,3-c]azepin-6-yl]propyl]piperidin-4-yl]-N-methylmethanesulfonamide
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|
C25H33Cl2N5O3S
|
1
|
| 1 |
IC50 = 2971 nM
|
|
|
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CP0563233
|
N-[1-[3-[5-(3,4-dichloroanilino)-1-oxo-2,6-naphthyridin-2-yl]propyl]piperidin-4-yl]-N-methylmethanesulfonamide
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|
C24H29Cl2N5O3S
|
1
|
| 1 |
IC50 = 3864 nM
|
|
|
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CP0563234
|
1-(3,4-dichloroanilino)-6-(3-morpholin-4-ylpropyl)-8,9-dihydro-7H-pyrido[4,3-c]azepin-5-one
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|
C22H26Cl2N4O2
|
1
|
| 1 |
IC50 = 4450 nM
|
|
|
|
CP0485566
|
N-[1-[3-[1-(3-fluoroanilino)-5-oxo-8,9-dihydro-7H-pyrido[4,3-c]azepin-6-yl]propyl]piperidin-4-yl]-N-methylmethanesulfonamide
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|
C25H34FN5O3S
|
1
|
| 1 |
IC50 = 4936 nM
|
|
|
|
CP0566423
|
N-[1-[3-[1-(4-tert-butylanilino)-5-oxo-8,9-dihydro-7H-pyrido[4,3-c]azepin-6-yl]propyl]piperidin-4-yl]-N-methylmethanesulfonamide
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|
C29H43N5O3S
|
1
|
| 1 |
IC50 = 5053 nM
|
|
|
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CP0478049
|
N-[1-[3-[1-[2-(3,4-dichlorophenyl)ethylamino]-5-oxo-8,9-dihydro-7H-pyrido[4,3-c]azepin-6-yl]propyl]piperidin-4-yl]-N-methylmethanesulfonamide
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|
C27H37Cl2N5O3S
|
1
|
| 1 |
IC50 = 7833 nM
|
|
|
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CP0389883
|
6-[3-(4-acetylpiperazin-1-yl)propyl]-1-(3,4-dichloroanilino)-8,9-dihydro-7H-pyrido[4,3-c]azepin-5-one
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|
C24H29Cl2N5O2
|
1
|
| 1 |
IC50 = 12330 nM
|
|
|
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CP0563235
|
1-(3,4-dichloroanilino)-6-[3-(4-methylpiperazin-1-yl)propyl]-8,9-dihydro-7H-pyrido[4,3-c]azepin-5-one
Show/Hide
|
C23H29Cl2N5O
|
1
|
| 1 |
IC50 = 19390 nM
|
|
|
