Brief Information of the Cell Line and Protein
Cell Line ID: CL000003 , Ramos
 Cell Line Info 
Synonyms
RAMOS
Ramos 1
RA 1
RA.1
Ra #1
Ra No. 1
Ramos(RA1)
Ramos-RA1
Ramos (RA 1)
Ramos (RA)
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0597
Protein ID: PT01006 , Cathepsin S
 Protein Info 
Gene Name CTSS
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P25774
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000003
 Cell Line Info 
 Protein ID: PT01006
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0146153
 Compound Info 
(2S)-N-(cyanomethyl)-3-cyclohexyl-2-(phenylformamido)propanamide
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C18H23N3O2
  1
1
IC50 = 10 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0091658
 Compound Info 
(S)-N-((S)-1-cyano-2-(4-cyano-2-fluorophenyl)ethyl)-3-methyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)butanamide
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C30H28F4N4O3S
  1
1
IC50 = 169 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0105431
 Compound Info 
(S)-N-((S)-1-cyano-2-(4-cyano-2-fluorophenyl)ethyl)-2-((S)-1-(4'-((R)-2,2-difluoro-1-hydroxyethyl)biphenyl-4-yl)-2,2,2-trifluoroethylamino)-3-methylbutanamide
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C31H28F6N4O2
  1
1
IC50 = 322 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0076420
 Compound Info 
1-(4'-((S)-1-((S)-1-((S)-1-cyano-2-(4-cyano-2-fluorophenyl)ethylamino)-3-methyl-1-oxobutan-2-ylamino)-2,2,2-trifluoroethyl)biphenyl-4-yl)cyclopropanecarboxamide
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C33H31F4N5O2
  1
1
IC50 = 408 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0134851
 Compound Info 
N-[1-(cyanomethylcarbamoyl)cyclohexyl]-4-[2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]benzamide
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C24H30N6O2S
  1
1
IC50 = 790 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0041940
 Compound Info 
(2R)-N-(cyanomethyl)-4-methyl-2-{3-[4-(piperazin-1-yl)phenyl]phenyl}pentanamide
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C24H30N4O
  1
1
IC50 = 1340 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0060236
 Compound Info 
Balicatib
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C23H33N5O2
  1
1
IC50 = 2900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0077259
 Compound Info 
N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-(morpholin-4-yl)benzamide
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C20H26N4O3
  1
1
IC50 = 4800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0077258
 Compound Info 
N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-[2-(morpholin-4-yl)-1,3-thiazol-4-yl]benzamide
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C23H27N5O3S
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS