| Compound ID |
Compound Name |
Compound Formula |
|
CP0402532
|
(S)-3-{(1R,3R)-3-[4-(2-Cyano-phenyl)-piperazin-1-yl]-cyclopentylcarbamoyl}-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
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|
C31H34F2N6O5
|
1
|
| 1 |
Ki = 5.4 nM
|
|
|
|
CP0432824
|
(S)-3-{(1R,3S)-3-[4-(2-Cyano-phenyl)-piperazin-1-yl]-cyclopentylcarbamoyl}-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
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|
C31H34F2N6O5
|
1
|
| 1 |
Ki = 7.5 nM
|
|
|
|
CP0445362
|
(S)-3-{(1S,3S)-3-[4-(2-Cyano-phenyl)-piperazin-1-yl]-cyclopentylcarbamoyl}-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
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|
C31H34F2N6O5
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0528362
|
(S)-3-{(1S,3S)-3-[4-(2-Cyano-phenyl)-piperidin-1-yl]-cyclopentylcarbamoyl}-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
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|
C32H35F2N5O5
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0463267
|
(S)-3-{(1R,3S)-3-[4-(2-Cyano-phenyl)-piperidin-1-yl]-cyclopentylcarbamoyl}-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
Show/Hide
|
C32H35F2N5O5
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0455391
|
(S)-3-{(1R,3R)-3-[4-(2-Cyano-phenyl)-piperidin-1-yl]-cyclopentylcarbamoyl}-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
Show/Hide
|
C32H35F2N5O5
|
1
|
| 1 |
Ki = 31 nM
|
|
|
|
CP0455350
|
(S)-3-{(1S,3R)-3-[4-(2-Cyano-phenyl)-piperazin-1-yl]-cyclopentylcarbamoyl}-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
Show/Hide
|
C31H34F2N6O5
|
1
|
| 1 |
Ki = 39 nM
|
|
|
|
CP0406359
|
(S)-3-[(1S,3S)-3-(4-Cyano-4-phenyl-piperidin-1-yl)-cyclopentylcarbamoyl]-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
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|
C32H35F2N5O5
|
1
|
| 1 |
Ki = 95 nM
|
|
|
|
CP0502347
|
(S)-3-{(1S,3R)-3-[4-(2-Cyano-phenyl)-piperidin-1-yl]-cyclopentylcarbamoyl}-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
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|
C32H35F2N5O5
|
1
|
| 1 |
Ki = 97 nM
|
|
|
|
CP0463780
|
(S)-4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-3-[(1S,3S)-3-(3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl-1'-yl)-cyclopentylcarbamoyl]-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
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|
C30H35F2N5O5
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0429286
|
(S)-4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-3-[(1R,3S)-3-(3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl-1'-yl)-cyclopentylcarbamoyl]-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
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|
C30H35F2N5O5
|
1
|
| 1 |
Ki = 320 nM
|
|
|
|
CP0502334
|
(S)-4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-3-[(1R,3R)-3-(3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl-1'-yl)-cyclopentylcarbamoyl]-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
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|
C30H35F2N5O5
|
1
|
| 1 |
Ki = 500 nM
|
|
|
|
CP0465015
|
(S)-4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-3-[(1S,3R)-3-(3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl-1'-yl)-cyclopentylcarbamoyl]-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
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|
C30H35F2N5O5
|
1
|
| 1 |
Ki = 550 nM
|
|
|
|
CP0463641
|
methyl (4S)-3-[[(1R,3S)-3-(4-cyano-4-phenylpiperidin-1-yl)cyclopentyl]carbamoyl]-4-(3,4-difluorophenyl)-6-(methoxymethyl)-2-oxo-1,4-dihydropyrimidine-5-carboxylate
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|
C32H35F2N5O5
|
1
|
| 1 |
Ki = 620 nM
|
|
|
|
CP0448487
|
(S)-3-[(1S,3R)-3-(4-Cyano-4-phenyl-piperidin-1-yl)-cyclopentylcarbamoyl]-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
Show/Hide
|
C32H35F2N5O5
|
1
|
| 1 |
Ki = 660 nM
|
|
|
|
CP0453018
|
(S)-3-[(1R,3R)-3-(4-Cyano-4-phenyl-piperidin-1-yl)-cyclopentylcarbamoyl]-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
Show/Hide
|
C32H35F2N5O5
|
1
|
| 1 |
Ki = 660 nM
|
|
|
