Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT00984 , Intermediate conductance calcium-activated potassium channel protein 4
 Protein Info 
Gene Name KCNN4
Organism Homo sapiens, Human
Protein Classification Ion channel
Uniprot ID O15554
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT00984
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0556217
 Compound Info 
4-[1-[4-fluoro-3-(trifluoromethoxy)phenyl]ethyl]-1,1-dioxothieno[3,2-b][1,4]thiazin-3-one
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C15H11F4NO4S2
  1
1
IC50 = 39 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0574316
 Compound Info 
4-[1-[3-(trifluoromethyl)phenyl]ethyl]pyrido[3,2-b][1,4]thiazin-3-one
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C16H13F3N2OS
  1
1
IC50 = 41 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0418549
 Compound Info 
1-[[4-fluoro-3-(trifluoromethoxy)phenyl]methyl]-4,4-dioxothieno[2,3-b][1,4]thiazin-2-one
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C14H9F4NO4S2
  1
1
IC50 = 48 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0556216
 Compound Info 
4-[[4-fluoro-3-(trifluoromethoxy)phenyl]methyl]-1,1-dioxopyrido[3,2-b][1,4]thiazin-3-one
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C15H10F4N2O4S
  1
1
IC50 = 49 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0556218
 Compound Info 
4-[[3-(trifluoromethoxy)phenyl]methyl]pyrido[3,2-b][1,4]thiazin-3-one
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C15H11F3N2O2S
  1
1
IC50 = 52 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0461368
 Compound Info 
7-[1-[4-fluoro-3-(trifluoromethoxy)phenyl]ethyl]-[1,3]thiazolo[4,5-b][1,4]thiazin-6-one
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C14H10F4N2O2S2
  1
1
IC50 = 60 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0386546
 Compound Info 
4-[[4-chloro-3-(trifluoromethyl)phenyl]methyl]-6-(hydroxymethyl)pyrido[3,2-b][1,4]thiazin-3-one
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C16H12ClF3N2O2S
  1
1
IC50 = 66 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0489984
 Compound Info 
4-[[4-fluoro-3-(trifluoromethoxy)phenyl]methyl]-7,7-dioxo-2-propan-2-yl-[1,3]thiazolo[5,4-b][1,4]thiazin-5-one
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C16H14F4N2O4S2
  1
1
IC50 = 96 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS