| Compound ID |
Compound Name |
Compound Formula |
|
CP0386534
|
(2S)-2-amino-N-[5-[[4-[[5-(3-hydroxypropylsulfanyl)-3-methyl-1-(2-methylpropyl)-4-oxopyrrolo[3,4-d]pyridazin-6-yl]methyl]isoquinolin-1-yl]amino]pentyl]pentanediamide
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|
C34H48N8O4S
|
1
|
| 1 |
EC50 = 0.16 nM
|
|
|
|
CP0399545
|
(2S)-2-amino-N-[5-[[4-[[5-(3-hydroxypropylsulfanyl)-3-methyl-1-(2-methylpropyl)-4-oxopyrrolo[3,4-d]pyridazin-6-yl]methyl]quinolin-2-yl]amino]pentyl]pentanediamide
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|
C34H48N8O4S
|
1
|
| 1 |
EC50 = 0.8 nM
|
|
|
|
CP0473519
|
(2S)-2-amino-3-[4-[5-[4-[[5-(3-hydroxypropylsulfanyl)-3-methyl-1-(2-methylpropyl)-4-oxopyrrolo[3,4-d]pyridazin-6-yl]methyl]naphthalen-1-yl]pent-4-ynoxy]phenyl]propanoic acid
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|
C39H44N4O5S
|
1
|
| 1 |
EC50 = 0.8 nM
|
|
|
|
CP0509819
|
6-[[1-(5-aminopentylamino)isoquinolin-4-yl]methyl]-5-(3-hydroxypropylsulfanyl)-3-methyl-1-(2-methylpropyl)pyrrolo[3,4-d]pyridazin-4-one
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|
C29H40N6O2S
|
1
|
| 1 |
EC50 = 0.8 nM
|
|
|
|
CP0407742
|
(2S)-2-amino-N-[5-[4-[[5-(3-hydroxypropylsulfanyl)-3-methyl-1-(2-methylpropyl)-4-oxopyrrolo[3,4-d]pyridazin-6-yl]methyl]naphthalen-1-yl]pent-4-ynyl]pentanediamide
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|
C35H44N6O4S
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0035405
|
7-[(3-hydroxypropyl)sulfanyl]-2-methyl-4-(2-methylpropyl)-6-(naphthalen-1-ylmethyl)-1H,2H,6H-pyrrolo[3,4-d]pyridazin-1-one
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|
C25H29N3O2S
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0398310
|
6-[(4-bromonaphthalen-1-yl)methyl]-5-(3-hydroxypropylsulfanyl)-3-methyl-1-(2-methylpropyl)pyrrolo[3,4-d]pyridazin-4-one
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|
C25H28BrN3O2S
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0567049
|
6-[[2-(5-aminopentylamino)quinolin-4-yl]methyl]-5-(3-hydroxypropylsulfanyl)-3-methyl-1-(2-methylpropyl)pyrrolo[3,4-d]pyridazin-4-one
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|
C29H40N6O2S
|
1
|
| 1 |
EC50 = 24 nM
|
|
|
|
CP0380615
|
6-[(1-chloroisoquinolin-4-yl)methyl]-5-(3-hydroxypropylsulfanyl)-3-methyl-1-(2-methylpropyl)pyrrolo[3,4-d]pyridazin-4-one
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|
C24H27ClN4O2S
|
1
|
| 1 |
EC50 = 55 nM
|
|
|
|
CP0454999
|
6-[(2-chloroquinolin-4-yl)methyl]-5-(3-hydroxypropylsulfanyl)-3-methyl-1-(2-methylpropyl)pyrrolo[3,4-d]pyridazin-4-one
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|
C24H27ClN4O2S
|
1
|
| 1 |
EC50 = 60 nM
|
|
|
|
CP0509821
|
(2S)-2-amino-N-[5-[[5-[[5-(3-hydroxypropylsulfanyl)-3-methyl-1-(2-methylpropyl)-4-oxopyrrolo[3,4-d]pyridazin-6-yl]methyl]pyridin-2-yl]amino]pentyl]pentanediamide
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|
C30H46N8O4S
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0386475
|
6-[[6-(5-aminopentylamino)pyridin-3-yl]methyl]-5-(3-hydroxypropylsulfanyl)-3-methyl-1-(2-methylpropyl)pyrrolo[3,4-d]pyridazin-4-one
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|
C25H38N6O2S
|
1
|
| 1 |
EC50 = 420 nM
|
|
|
|
CP0386476
|
(2S)-2-amino-N-[5-[[4-[[5-(3-hydroxypropylsulfanyl)-3-methyl-1-(2-methylpropyl)-4-oxopyrrolo[3,4-d]pyridazin-6-yl]methyl]pyridin-2-yl]amino]pentyl]pentanediamide
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|
C30H46N8O4S
|
1
|
| 1 |
EC50 = 500 nM
|
|
|
|
CP0509818
|
6-[[2-(5-aminopentylamino)pyridin-4-yl]methyl]-5-(3-hydroxypropylsulfanyl)-3-methyl-1-(2-methylpropyl)pyrrolo[3,4-d]pyridazin-4-one
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|
C25H38N6O2S
|
1
|
| 1 |
EC50 = 520 nM
|
|
|
|
CP0376798
|
6-[(6-chloropyridin-3-yl)methyl]-5-(3-hydroxypropylsulfanyl)-3-methyl-1-(2-methylpropyl)pyrrolo[3,4-d]pyridazin-4-one
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|
C20H25ClN4O2S
|
1
|
| 1 |
EC50 = 690 nM
|
|
|
|
CP0545098
|
6-[(2-chloropyridin-4-yl)methyl]-5-(3-hydroxypropylsulfanyl)-3-methyl-1-(2-methylpropyl)pyrrolo[3,4-d]pyridazin-4-one
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|
C20H25ClN4O2S
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
