Brief Information of the Cell Line and Protein
Cell Line ID: CL000652 , KM12
Synonyms
KM-12
KM.12
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1331
Protein ID: PT00934 , High affinity nerve growth factor receptor
Gene Name NTRK1
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P04629
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000652  Protein ID: PT00934
 
Compound ID Compound Name Compound Formula
CP0385508
2-[4-[4-[6-[(2R)-2-(3-fluorophenyl)pyrrolidin-1-yl]imidazo[1,2-b]pyridazin-3-yl]pyridin-2-yl]piperazin-1-yl]acetic acid
   Show/Hide
C27H28FN7O2
 1
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
CP0385511
1-[4-[6-[(2R)-2-(3-fluorophenyl)pyrrolidin-1-yl]imidazo[1,2-b]pyridazin-3-yl]pyridin-2-yl]piperidin-4-ol
   Show/Hide
C26H27FN6O
 1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS