(3S,6S,9R,12S,15S,23S)-15-((S)-2-acetylamino-hexanoylamino)-9-benzyl-6-(3-guanidino-propyl)-12-(3H-imidazol-4-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18hexaaza-cyclotricosane-23-carboxylic acid amide

2-[(1R,4S,10S,13S,16S,19S,22S,25S,28R,31S,34S,37S,40S,43S,49Z)-49-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethylamino]-2-oxo-ethoxy]imino-13,34-dibenzyl-4-butyl-16,25,37,43-tetrakis(3-guanidinopropyl)-10,31-bis(1H-imidazol-5-ylmethyl)-19,40-bis(1H-indol-3-ylmethyl)-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44-pentadecaoxo-47,51-dithia-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-pentadecazabicyclo[26.17.7]dopentacontan-22-yl]acetic acid

BREMELANOTIDE

2-[(1R,4S,7S,10S,13S,16S,19S,25S,28R,31S,34S,37S,40S,43S)-16,40-dibenzyl-25-butyl-4,13,31,37-tetrakis(3-carbamimidamidopropyl)-50-hex-5-ynyl-19,43-bis(1H-imidazol-5-ylmethyl)-10,34-bis(1H-indol-3-ylmethyl)-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,49,51-heptadecaoxo-47,53-dithia-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,50-hexadecazatricyclo[26.17.9.048,52]tetrapentacont-48(52)-en-7-yl]acetic acid

2-[(1R,4S,7S,10S,13S,16S,19S,25S,28R,31S,34S,37S,40S,43S)-16,40-dibenzyl-25-butyl-4,13,31,37-tetrakis(3-carbamimidamidopropyl)-19,43-bis(1H-imidazol-5-ylmethyl)-10,34-bis(1H-indol-3-ylmethyl)-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-pentadecaoxo-47,55-dithia-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44-pentadecazatricyclo[26.17.11.149,53]heptapentaconta-49,51,53(57)-trien-7-yl]acetic acid

2-[(1R,4S,7S,10S,13S,16S,19S,25S,28R,31S,34S,37S,40S,43S)-16,40-dibenzyl-25-butyl-4,13,31,37-tetrakis(3-carbamimidamidopropyl)-19,43-bis(1H-imidazol-5-ylmethyl)-10,34-bis(1H-indol-3-ylmethyl)-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-pentadecaoxo-47,54-dithia-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44-pentadecazatricyclo[26.17.10.249,52]heptapentaconta-49,51,56-trien-7-yl]acetic acid

3-[2-[2-[2-[2-[[(1R,4S,7S,10S,13S,16S,19S,25S,28R,31S,34S,37S,40S,43S)-16,40-dibenzyl-25-butyl-4,13,31,37-tetrakis(3-carbamimidamidopropyl)-7-(carboxymethyl)-19,43-bis(1H-imidazol-5-ylmethyl)-10,34-bis(1H-indol-3-ylmethyl)-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-pentadecaoxo-47,59-dithia-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,61,62-heptadecazapentacyclo[26.17.15.248,58.049,57.052,54]dohexaconta-48(62),49(57),58(61)-trien-53-yl]methoxycarbonylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

2-[(1R,4S,7S,10S,13S,16S,19S,25S,28R,31S,34S,37S,40S,43S)-16,40-dibenzyl-25-butyl-4,13,31,37-tetrakis(3-carbamimidamidopropyl)-49,50,54,55-tetrafluoro-19,43-bis(1H-imidazol-5-ylmethyl)-10,34-bis(1H-indol-3-ylmethyl)-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-pentadecaoxo-47,52-dithia-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44-pentadecazatricyclo[26.17.8.248,51]pentapentaconta-48,50,54-trien-7-yl]acetic acid

2-[(1R,4S,10S,13S,16S,19S,22S,25S,28R,31S,34S,37S,40S,43S)-13,34-dibenzyl-4-butyl-16,25,37,43-tetrakis(3-guanidinopropyl)-10,31-bis(1H-imidazol-5-ylmethyl)-19,40-bis(1H-indol-3-ylmethyl)-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44-pentadecaoxo-47,48-dithia-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-pentadecazabicyclo[26.17.4]nonatetracontan-22-yl]acetic acid

SETMELANOTIDE

2-[(1R,4S,7S,10S,13S,16S,19S,25S,28R,31S,34S,37S,40S,43S)-16,40-dibenzyl-25-butyl-4,13,31,37-tetrakis(3-carbamimidamidopropyl)-19,43-bis(1H-imidazol-5-ylmethyl)-10,34-bis(1H-indol-3-ylmethyl)-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-pentadecaoxo-47,56-dithia-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44-pentadecazatricyclo[26.17.12.049,54]heptapentaconta-49,51,53-trien-7-yl]acetic acid

2-[(1R,4S,7S,10S,13S,16S,19S,25S,28R,31S,34S,37S,40S,43S)-16,40-dibenzyl-25-butyl-4,13,31,37-tetrakis(3-carbamimidamidopropyl)-19,43-bis(1H-imidazol-5-ylmethyl)-10,34-bis(1H-indol-3-ylmethyl)-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,49,51-heptadecaoxo-47,53-dithia-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,50-hexadecazatricyclo[26.17.9.048,52]tetrapentacont-48(52)-en-7-yl]acetic acid

2-((1R,4S,7S,10S,13S,16S,19S,25S,28R,31S,34S,37S,40S,43S)-19,43-bis((1H-imidazol-5-yl)methyl)-10,34-bis((1H-indol-3-yl)methyl)-16,40-dibenzyl-25-butyl-4,13,31,37-tetrakis(3-guanidinopropyl)-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-pentadecaoxo-47,48-dithia-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44-pentadecaazabicyclo[26.17.4]nonatetracontan-7-yl)acetic acid

(1R,4S,7S,10S,13S,16S,19S,25S,28R,31S,34S,37S,40S,43S,48Z)-16,40-dibenzyl-25-butyl-48-carbamoyl-7-(carboxymethyl)-4,13,31,37-tetrakis(3-guanidinopropyl)-19,43-bis(1H-imidazol-5-ylmethyl)-10,34-bis(1H-indol-3-ylmethyl)-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-pentadecaoxo-47,50-dithia-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44-pentadecazabicyclo[26.17.6]henpentacont-48-ene-49-carboxylic acid

2-[(1R,4S,10S,13S,16S,19S,22S,25S,28R,31S,34S,37S,40S,43S)-13,34-dibenzyl-4-butyl-16,25,37,43-tetrakis(3-guanidinopropyl)-10,31-bis(1H-imidazol-5-ylmethyl)-19,40-bis(1H-indol-3-ylmethyl)-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,49-hexadecaoxo-47,51-dithia-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-pentadecazabicyclo[26.17.7]dopentacontan-22-yl]acetic acid

(12S,4S,7R,17R,20S,23S,26S,29S,32S)-23-((1H-imidazol-5-yl)methyl)-32-((1H-indol-3-yl)methyl)-17-acetamido-26-benzyl-4-((S)-sec-butyl)-29-(3-guanidinopropyl)-20-((R)-1-hydroxyethyl)-28-methyl-2,5,18,21,24,27,30,33-octaoxo-10,14-dithia-3,6,19,22,25,28,31-heptaaza-1(2,1)-pyrrolidina-12(1,3)-benzenacyclotritriacontaphane-7-carboxamide

(6S,9S,12S,15S,18S,21R,32R,35S,37aS)-15-((1H-imidazol-5-yl)methyl)-6-((1H-indol-3-yl)methyl)-21-acetamido-12-benzyl-35-((S)-sec-butyl)-9-(3-guanidinopropyl)-18-((R)-1-hydroxyethyl)-10-methyl-5,8,11,14,17,20,34,37-octaoxo-2,3,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,24,29,31,32,33,34,35,36,37,37a-triacontahydro-1H-benzo[e1]pyrrolo[2,1-i][1,29]dithia[4,7,10,13,16,19,22,25]octaazacyclotritriacontine-32-carboxamide

(6S,9S,12S,15S,18S,21R,34R,37S,39aS)-15-((1H-imidazol-5-yl)methyl)-6-((1H-indol-3-yl)methyl)-21-acetamido-12-benzyl-37-((S)-sec-butyl)-9-(3-guanidinopropyl)-18-((R)-1-hydroxyethyl)-10-methyl-5,8,11,14,17,20,36,39-octaoxo-1,2,3,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,25,30,32,33,34,35,36,37,38,39,39a-dotriacontahydro-5H-benzo[g1]pyrrolo[2,1-j][1,31]dithia[5,8,11,14,17,20,23,26]octaazacyclopentatriacontine-34-carboxamide

(12S,4S,7R,15R,18S,21S,24S,27S,30S)-21-((1H-imidazol-5-yl)methyl)-30-((1H-indol-3-yl)methyl)-15-acetamido-24-benzyl-4-((S)-sec-butyl)-27-(3-guanidinopropyl)-18-((R)-1-hydroxyethyl)-26-methyl-2,5,16,19,22,25,28,31-octaoxo-9,13-dithia-3,6,17,20,23,26,29-heptaaza-1(2,1)-pyrrolidina-11(1,3)-benzenacyclohentriacontaphane-7-carboxamide

(12S,4S,7R,17R,20S,23S,26S,29S,32S)-23-((1H-imidazol-5-yl)methyl)-32-((1H-indol-3-yl)methyl)-17-acetamido-26-benzyl-4-((S)-sec-butyl)-29-(3-guanidinopropyl)-20-((R)-1-hydroxyethyl)-28-methyl-2,5,18,21,24,27,30,33-octaoxo-10,14-dithia-3,6,19,22,25,28,31-heptaaza-1(2,1)-pyrrolidina-12(1,4)-benzenacyclotritriacontaphane-7-carboxamide

(3S,6R,13R,16S,19S,22S,25S,28S,33aS)-19-((1H-imidazol-5-yl)methyl)-28-((1H-indol-3-yl)methyl)-13-acetamido-22-benzyl-3-((S)-sec-butyl)-25-(3-guanidinopropyl)-16-((R)-1-hydroxyethyl)-24-methyl-1,4,14,17,20,23,26,29-octaoxotriacontahydro-11H-pyrrolo[2,1-k][1,2]dithia[6,9,12,15,18,21,24,27]octaazacyclohentriacontine-6-carboxamide

(12S,4S,7R,15R,18S,21S,24S,27S,30S)-21-((1H-imidazol-5-yl)methyl)-30-((1H-indol-3-yl)methyl)-15-acetamido-24-benzyl-4-((S)-sec-butyl)-27-(3-guanidinopropyl)-18-((R)-1-hydroxyethyl)-26-methyl-2,5,16,19,22,25,28,31-octaoxo-9,13-dithia-3,6,17,20,23,26,29-heptaaza-1(2,1)-pyrrolidina-11(1,4)-benzenacyclohentriacontaphane-7-carboxamide

(3S,6S,9S,12S,15S,18R,23R,26S,29S)-18-acetamido-9-benzyl-6-(3-guanidinopropyl)-15-[(1R)-1-hydroxyethyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-7-methyl-26-[(1S)-1-methylpropyl]-2,5,8,11,14,17,25,28-octaoxo-20,21-dithia-1,4,7,10,13,16,24,27-octazabicyclo[27.3.0]dotriacontane-23-carboxamide