Brief Information of the Cell Line and Protein
Cell Line ID: CL000012 , Sf21
 Cell Line Info 
Synonyms
SF21
Sf-21
SF-21
IPLB-SF-21-AE
IPLB-Sf21-AE
IPLB-SF21-AE
IPLB-SF 21AE
IPLB-Sf21AE
IPLB-SF21AE
IPLB-SF-21
IPLB-Sf-21
IPLB-SF 21
IPLB-Sf21
IPLB-SF21
Category Spontaneously immortalized cell line
Organism
Spodoptera frugiperda (Fall armyworm)
Cellosaurus ID
CVCL_0518
Protein ID: PT00879 , Proto-oncogene tyrosine-protein kinase Src
 Protein Info 
Gene Name SRC
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P12931
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000012
 Cell Line Info 
 Protein ID: PT00879
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0065733
 Compound Info 
2-[[N-[2-[3-ethylsulfonyl-4-(4-methylpiperazin-1-yl)anilino]-5-fluoropyrimidin-4-yl]-5-(hydroxymethyl)-2-methylanilino]methyl]benzonitrile
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C33H36FN7O3S
  1
1
IC50 = 93 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0072678
 Compound Info 
5-(1,3-benzodioxol-5-yl)-7-[[(2R)-1-ethenylsulfonylpyrrolidin-2-yl]methyl]pyrrolo[2,3-d]pyrimidin-4-amine
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C20H21N5O4S
  1
1
IC50 = 197 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0247128
 Compound Info 
N-benzyl-7-[(4-fluorophenyl)methyl]-2-methylsulfanylpyrrolo[2,3-d]pyrimidin-4-amine
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C21H19FN4S
  1
1
Ki = 500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0247129
 Compound Info 
N-(3-chlorophenyl)-7-(2-chloro-2-phenylethyl)-2-methylsulfanylpyrrolo[2,3-d]pyrimidin-4-amine
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C21H18Cl2N4S
  1
1
Ki = 700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0247131
 Compound Info 
7-[(4-fluorophenyl)methyl]-2-methylsulfanyl-N-(2-phenylethyl)pyrrolo[2,3-d]pyrimidin-4-amine
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C22H21FN4S
  1
1
Ki = 800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0262311
 Compound Info 
7-(2-chloro-2-phenylethyl)-2-methylsulfanyl-N-phenylpyrrolo[2,3-d]pyrimidin-4-amine
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C21H19ClN4S
  1
1
Ki = 1500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0119015
 Compound Info 
7-[(4-fluorophenyl)methyl]-2-methylsulfanyl-4-pyrrolidin-1-ylpyrrolo[2,3-d]pyrimidine
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C18H19FN4S
  1
1
Ki = 2000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0113832
 Compound Info 
7-[(4-fluorophenyl)methyl]-2-methylsulfanyl-4-piperidin-1-ylpyrrolo[2,3-d]pyrimidine
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C19H21FN4S
  1
1
Ki = 2500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0214987
 Compound Info 
N-butyl-7-[(4-fluorophenyl)methyl]-2-methylsulfanylpyrrolo[2,3-d]pyrimidin-4-amine
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C18H21FN4S
  1
1
Ki = 3000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0250718
 Compound Info 
4-[7-[(4-fluorophenyl)methyl]-2-methylsulfanylpyrrolo[2,3-d]pyrimidin-4-yl]morpholine
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C18H19FN4OS
  1
1
Ki = 4700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0214989
 Compound Info 
N-[2-(4-chlorophenyl)ethyl]-7-[(4-fluorophenyl)methyl]-2-methylsulfanylpyrrolo[2,3-d]pyrimidin-4-amine
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C22H20ClFN4S
  1
1
Ki = 5000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0119014
 Compound Info 
N-benzyl-7-(2-chloro-2-phenylethyl)-2-methylsulfanylpyrrolo[2,3-d]pyrimidin-4-amine
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C22H21ClN4S
  1
1
Ki = 6000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS