| Compound ID |
Compound Name |
Compound Formula |
|
CP0567322
|
4-[(7'-cyclopentyl-6'-oxospiro[cyclopropane-1,5'-pyrrolo[2,3-d]pyrimidine]-2'-yl)amino]benzenesulfonamide
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|
C19H21N5O3S
|
2
|
| 1 |
IC50 = 4.9 nM
|
|
|
| 2 |
IC50 = 7600 nM
|
|
|
|
CP0567595
|
4-[[7'-[(1R,2R)-2-methylcyclopentyl]-6'-oxospiro[cyclopropane-1,5'-pyrrolo[2,3-d]pyrimidine]-2'-yl]amino]-N-[(3R)-1-methylpiperidin-3-yl]benzenesulfonamide
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|
C26H34N6O3S
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0573919
|
US11384083, Example 2
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|
C19H27N5O3S
|
1
|
| 1 |
IC50 = 102 nM
|
|
|
|
CP0577706
|
N-methyl-4-[[7'-[(1S,2S)-2-methylcyclopentyl]-6'-oxospiro[cyclopropane-1,5'-pyrrolo[2,3-d]pyrimidine]-2'-yl]amino]benzenesulfonamide
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|
C21H25N5O3S
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0579094
|
US11384083, Example 12
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|
C23H31N7O4S
|
1
|
| 1 |
IC50 = 316 nM
|
|
|
|
CP0579093
|
4-[[7'-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]-6'-oxospiro[cyclopropane-1,5'-pyrrolo[2,3-d]pyrimidine]-2'-yl]amino]-N-methylbenzenesulfonamide
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|
C21H25N5O4S
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0572640
|
4-[[7'-(2-chloro-5-fluorophenyl)-6'-oxospiro[cyclopropane-1,5'-pyrrolo[2,3-d]pyrimidine]-2'-yl]amino]-N-methylbenzenesulfonamide
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|
C21H17ClFN5O3S
|
1
|
| 1 |
IC50 = 460 nM
|
|
|
|
CP0580140
|
4-[[7'-[(1S)-1-cyclopropylethyl]-6'-oxospiro[cyclopropane-1,5'-pyrrolo[2,3-d]pyrimidine]-2'-yl]amino]-N-methylbenzenesulfonamide
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|
C20H23N5O3S
|
1
|
| 1 |
IC50 = 460 nM
|
|
|
|
CP0842129
|
4-((7'-((1R,3R)-3-Hydroxycyclohexyl)-6'-oxo-6',7'-dihydrospiro[cyclopropane-1,5'-pyrrolo[2,3-d]pyrimidin]-2'-yl)amino)-N-(methyl-d3)benzenesulfonamide
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|
C21H25N5O4S
|
1
|
| 1 |
IC50 = 642 nM
|
|
|
|
CP0577498
|
4-[[7'-[(1R,3R)-3-hydroxycyclohexyl]-6'-oxospiro[cyclopropane-1,5'-pyrrolo[2,3-d]pyrimidine]-2'-yl]amino]-N-methylbenzenesulfonamide
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|
C21H25N5O4S
|
1
|
| 1 |
IC50 = 670 nM
|
|
|
|
CP0842128
|
4-((7'-((cis)-2-Hydroxy-2-methylcyclopentyl)-6'-oxo-6',7'-dihydrospiro[cyclopropane-1,5'-pyrrolo[2,3-d]pyrimidin]-2'-yl)amino)-N-(methyl-d3)benzenesulfonamide
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|
C21H25N5O4S
|
1
|
| 1 |
IC50 = 746 nM
|
|
|
|
CP0577707
|
N-(2-hydroxyethyl)-4-[[7'-[(1R,2R)-2-methylcyclopentyl]-6'-oxospiro[cyclopropane-1,5'-pyrrolo[2,3-d]pyrimidine]-2'-yl]amino]benzenesulfonamide
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|
C22H27N5O4S
|
1
|
| 1 |
IC50 = 770 nM
|
|
|
