Brief Information of the Compound and Protein
Compound Name
4-[(7'-cyclopentyl-6'-oxospiro[cyclopropane-1,5'-pyrrolo[2,3-d]pyrimidine]-2'-yl)amino]benzenesulfonamide
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PubChem ID
CID: 168278877
Canonical SMILES
NS(=O)(=O)c1ccc(Nc2ncc3c(n2)N(C2CCCC2)C(=O)C32CC2)cc1
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Compound Formula C19H21N5O3S
Compound Structure
Protein Name
Cyclin-dependent kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase CDK family
>
CMGC protein kinase CDC2 subfamily
Uniprot ID
P24941
Gene Name
CDK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000713 COV318 Homo sapiens (Human)  2
1
IC50 = 4.9 nM
   TI
   LI
   LO
   TS
2
IC50 = 7600 nM
   TI
   LI
   LO
   TS