Brief Information of the Cell Line and Protein
Cell Line ID: CL000090 , Schneider 2
 Cell Line Info 
Synonyms
S2
S-2
SC-2
SL-2
SL2
Line 2
Schneider's Line S2
Schneider's line 2
Schneider Line 2
Schneider L2
Schneider's Drosophila Line2
SCHNEIDER-2
SCHNEIDER S2
Schneider S2
Drosophila Line 2
D. mel. (2)
D.Mel-2
D.mel-2
WR69-DM-2
WR-DM-2
Dm2
DL2
S2-ATCC
S2-Invitrogen
S2-RIKEN
S2U
Category Spontaneously immortalized cell line
Organism
Drosophila melanogaster (Fruit fly)
Cellosaurus ID
CVCL_Z232
Protein ID: PT00845 , RAC-alpha serine/threonine-protein kinase
 Protein Info 
Gene Name AKT1
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P31749
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000090
 Cell Line Info 
 Protein ID: PT00845
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0266030
 Compound Info 
9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triazol-3-yl)piperidin-1-yl)methyl)phenyl)-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-ol
   Show/Hide
C34H29N9O
  1
1
IC50 = 2.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0370959
 Compound Info 
9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triazol-3-yl)piperidin-1-yl)methyl)phenyl)-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-amine
   Show/Hide
C34H30N10
  1
1
IC50 = 2.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0497955
 Compound Info 
9-phenyl-8-(4-((4-(4-(pyridin-2-yl)-1H-imidazol-1-yl)piperidin-1-yl)methyl)phenyl)-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-amine
   Show/Hide
C35H31N9
  1
1
IC50 = 3.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0039577
 Compound Info 
9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triazol-3-yl)piperidin-1-yl)methyl)phenyl)-[1,2,4]triazolo[3,4-f][1,6]naphthyridine
   Show/Hide
C34H29N9
  1
1
IC50 = 4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0293543
 Compound Info 
3-methyl-9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triazol-3-yl)piperidin-1-yl)methyl)phenyl)-[1,2,4]triazolo[3,4-f][1,6]naphthyridine
   Show/Hide
C35H31N9
  1
1
IC50 = 4.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0318762
 Compound Info 
1-(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triazol-3-yl)piperidin-1-yl)methyl)phenyl)-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-yl)urea
   Show/Hide
C35H31N11O
  1
1
IC50 = 8.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0293542
 Compound Info 
3-((4-methylpiperazin-1-yl)methyl)-9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triazol-3-yl)piperidin-1-yl)methyl)phenyl)-[1,2,4]triazolo[3,4-f][1,6]naphthyridine
   Show/Hide
C40H41N11
  1
1
IC50 = 9.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0370958
 Compound Info 
9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triazol-3-yl)piperidin-1-yl)methyl)phenyl)-[1,2,4]triazolo[3,4-f][1,6]naphthyridine-3-thiol
   Show/Hide
C34H29N9S
  1
1
IC50 = 10 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0353733
 Compound Info 
2-((9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triazol-3-yl)piperidin-1-yl)methyl)phenyl)-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-yl)methylamino)ethanol
   Show/Hide
C37H36N10O
  1
1
IC50 = 17 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0279700
 Compound Info 
3-(chloromethyl)-9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triazol-3-yl)piperidin-1-yl)methyl)phenyl)-[1,2,4]triazolo[3,4-f][1,6]naphthyridine
   Show/Hide
C35H30ClN9
  1
1
IC50 = 26.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS