Brief Information of the Cell Line and Protein
Cell Line ID: CL000118 , U-251MG
 Cell Line Info 
Synonyms
U-251 MG
U-251-MG
U-251_MG
U251-MG
U251MG
U-251
U251
U251n
U251N
251 MG
251MG
251 MG(6)
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0021
Protein ID: PT00844 , Platelet-derived growth factor receptor beta
 Protein Info 
Gene Name PDGFRB
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P09619
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000118
 Cell Line Info 
 Protein ID: PT00844
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0383276
 Compound Info 
N-(4-methoxyphenyl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
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C16H17N3O2
  1
1
IC50 = 22.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0432230
 Compound Info 
N-(2,3-dihydro-1-benzofuran-5-yl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
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C17H17N3O2
  1
1
IC50 = 24.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0425261
 Compound Info 
N-(1-benzofuran-5-yl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
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C17H15N3O2
  1
1
IC50 = 25 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0388586
 Compound Info 
N-(2,4-dimethoxyphenyl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
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C17H19N3O3
  1
1
IC50 = 40.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0398717
 Compound Info 
N-(1,3-benzodioxol-5-yl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
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C16H15N3O3
  1
1
IC50 = 50.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0504740
 Compound Info 
4-(6-methoxy-3,4-dihydro-2H-quinolin-1-yl)-2,6-dimethylfuro[2,3-d]pyrimidine
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C18H19N3O2
  1
1
IC50 = 58.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0379500
 Compound Info 
N-(3,4-dimethoxyphenyl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
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C17H19N3O3
  1
1
IC50 = 66.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0488682
 Compound Info 
4-(5-methoxy-2,3-dihydroindol-1-yl)-2,6-dimethylfuro[2,3-d]pyrimidine
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C17H17N3O2
  1
1
IC50 = 73.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0002211
 Compound Info 
N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
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C22H27FN4O2
  1
1
IC50 = 83.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0431419
 Compound Info 
N,2,6-trimethyl-N-(4-propan-2-yloxyphenyl)furo[2,3-d]pyrimidin-4-amine
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C18H21N3O2
  1
1
IC50 = 84 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0504741
 Compound Info 
N-(4-ethoxyphenyl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
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C17H19N3O2
  1
1
IC50 = 132 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0418650
 Compound Info 
N,2,6-trimethyl-N-(3,4,5-trimethoxyphenyl)furo[2,3-d]pyrimidin-4-amine
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C18H21N3O4
  1
1
IC50 = 166.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0488677
 Compound Info 
4-(5-methoxyindol-1-yl)-2,6-dimethylfuro[2,3-d]pyrimidine
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C17H15N3O2
  1
1
IC50 = 198 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS