Brief Information of the Cell Line and Protein
Cell Line ID: CL000109 , COS-1
 Cell Line Info 
Synonyms
Cos-1
COS 1
Cos 1
COS1
Cos1
CV-1 in Origin Simian-1
Category Transformed cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0223
Protein ID: PT00819 , 5-hydroxytryptamine receptor 1A
 Protein Info 
Gene Name HTR1A
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P08908
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000109
 Cell Line Info 
 Protein ID: PT00819
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0380890
 Compound Info 
N,N'-bis(8-methoxyquinolin-4-yl)heptane-1,7-diamine
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C27H32N4O2
  1
1
Ki = 603 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0406153
 Compound Info 
N,N'-bis(6-methylquinolin-4-yl)ethane-1,2-diamine
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C22H22N4
  1
1
Ki = 617 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0379153
 Compound Info 
Bivalent 4-Aminoquinoline 9f
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C25H28N4
  1
1
Ki = 832 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0379133
 Compound Info 
N,N'-bis(7-methoxyquinolin-4-yl)ethane-1,2-diamine
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C22H22N4O2
  1
1
Ki = 891 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0406151
 Compound Info 
N,N'-bis(6-methylquinolin-4-yl)heptane-1,7-diamine
   Show/Hide
C27H32N4
  1
1
Ki = 1096 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0379752
 Compound Info 
N,N'-bis(8-methylquinolin-4-yl)ethane-1,2-diamine
   Show/Hide
C22H22N4
  1
1
Ki = 1175 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0379155
 Compound Info 
N,N'-bis(7-methylquinolin-4-yl)heptane-1,7-diamine
   Show/Hide
C27H32N4
  1
1
Ki = 1259 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0379151
 Compound Info 
N,N'-bis(6-methoxyquinolin-4-yl)heptane-1,7-diamine
   Show/Hide
C27H32N4O2
  1
1
Ki = 1380 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0379156
 Compound Info 
N,N'-di(quinolin-4-yl)ethane-1,2-diamine
   Show/Hide
C20H18N4
  1
1
Ki = 2291 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0379444
 Compound Info 
N,N'-bis(7-methoxyquinolin-4-yl)heptane-1,7-diamine
   Show/Hide
C27H32N4O2
  1
1
Ki = 2818 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0379149
 Compound Info 
N,N'-bis(8-methoxyquinolin-4-yl)ethane-1,2-diamine
   Show/Hide
C22H22N4O2
  1
1
Ki = 3090 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0413448
 Compound Info 
N,N'-bis(7-methylquinolin-4-yl)ethane-1,2-diamine
   Show/Hide
C22H22N4
  1
1
Ki = 3467 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS