General Information of the Compound
Compound ID
CP0957587
Compound Name
MOTILIN_062
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Structure
Formula
C27H34FN5S
Molecular Weight
479.669
Canonical SMILES
C[C@@H]1CN(Cc2ccc(-c3cccnc3N3CCC(Nc4ccc(F)cc4)CC3)s2)C[C@H](C)N1
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InChI
InChI=1S/C27H34FN5S/c1-19-16-32(17-20(2)30-19)18-24-9-10-26(34-24)25-4-3-13-29-27(25)33-14-11-23(12-15-33)31-22-7-5-21(28)6-8-22/h3-10,13,19-20,23,30-31H,11-12,14-18H2,1-2H3/t19-,20+
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InChIKey
PXHGUNWOKOBEKV-BGYRXZFFSA-N
Physicochemical Property
logP
5.2123
Rotatable Bonds
6
Heavy Atom Count
34
Polar Areas
43.43
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 16749728
SID: 26735833
ChEMBL ID
CHEMBL2364324
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01121, Motilin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 25.12 nM
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