General Information of the Compound
Compound ID
CP0957432
Compound Name
(R)-2-({1-[2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]ethyl}(butyl)amino)-N-ethyl-N-methylbenzo[d]oxazole-4-carboxamide
    Show/Hide
Formula
C30H33N7O2
Molecular Weight
523.641
Canonical SMILES
CCCCN(c1nc2c(C(=O)N(C)CC)cccc2o1)[C@H](C)c1ccc(-c2ccccc2-c2nnn[nH]2)cc1
    Show/Hide
InChI
InChI=1S/C30H33N7O2/c1-5-7-19-37(30-31-27-25(29(38)36(4)6-2)13-10-14-26(27)39-30)20(3)21-15-17-22(18-16-21)23-11-8-9-12-24(23)28-32-34-35-33-28/h8-18,20H,5-7,19H2,1-4H3,(H,32,33,34,35)/t20-/m1/s1
    Show/Hide
InChIKey
IAYJJCMJRDALQD-HXUWFJFHSA-N
Physicochemical Property
logP
6.1345
Rotatable Bonds
10
Heavy Atom Count
39
Polar Areas
104.04
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
39

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
ChEMBL ID
CHEMBL4741497
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03813, Chemerin-like receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000681 CAL-1 [Human melanoma] Homo sapiens (Human)  1
1
IC50 = 62 nM
   TI
   LI
   LO
   TS