General Information of the Compound
Compound ID
CP0953941
Compound Name
1-[(2-Bromophenyl)sulfonyl]-3-[(1-piperazinyl)methyl]-1H-indole Dihydrochloride
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Structure
Formula
C19H22BrCl2N3O2S
Molecular Weight
507.281
Canonical SMILES
Cl.Cl.O=S(=O)(c1ccccc1Br)n1cc(CN2CCNCC2)c2ccccc21
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InChI
InChI=1S/C19H20BrN3O2S.2ClH/c20-17-6-2-4-8-19(17)26(24,25)23-14-15(13-22-11-9-21-10-12-22)16-5-1-3-7-18(16)23;;/h1-8,14,21H,9-13H2;2*1H
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InChIKey
HPZWMYMORUFPFU-UHFFFAOYSA-N
Physicochemical Property
logP
3.8896
Rotatable Bonds
4
Heavy Atom Count
28
Polar Areas
54.34
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 137650747
ChEMBL ID
CHEMBL4077537
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 4.5 nM
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