General Information of the Compound
Compound ID
CP0948409
Compound Name
1-Benzenesulfonyl-(4-piperazin-1-ylmethyl)-1H-indole dihydrochloride
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Structure
Formula
C19H23Cl2N3O2S
Molecular Weight
428.385
Canonical SMILES
Cl.Cl.O=S(=O)(c1ccccc1)n1ccc2c(CN3CCNCC3)cccc21
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InChI
InChI=1S/C19H21N3O2S.2ClH/c23-25(24,17-6-2-1-3-7-17)22-12-9-18-16(5-4-8-19(18)22)15-21-13-10-20-11-14-21;;/h1-9,12,20H,10-11,13-15H2;2*1H
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InChIKey
HSGHYLUOCCBBRG-UHFFFAOYSA-N
Physicochemical Property
logP
3.1271
Rotatable Bonds
4
Heavy Atom Count
27
Polar Areas
54.34
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 24970038
SID: 56268196
ChEMBL ID
CHEMBL3216565
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 7.84 nM
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