General Information of the Compound
Compound ID
CP0948273
Compound Name
{4-[1-(2-Bromobenzenesulfonyl)-1H-indol-3-ylmethyl]piperazin-1-yl}phenylmethanone Hydrochloride
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Structure
Formula
C26H25BrClN3O3S
Molecular Weight
574.928
Canonical SMILES
Cl.O=C(c1ccccc1)N1CCN(Cc2cn(S(=O)(=O)c3ccccc3Br)c3ccccc23)CC1
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InChI
InChI=1S/C26H24BrN3O3S.ClH/c27-23-11-5-7-13-25(23)34(32,33)30-19-21(22-10-4-6-12-24(22)30)18-28-14-16-29(17-15-28)26(31)20-8-2-1-3-9-20;/h1-13,19H,14-18H2;1H
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InChIKey
JHBVJTXODOPQIS-UHFFFAOYSA-N
Physicochemical Property
logP
5.0206
Rotatable Bonds
5
Heavy Atom Count
35
Polar Areas
62.62
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
5
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 137662324
ChEMBL ID
CHEMBL4099525
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 365 nM
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