General Information of the Compound
Compound ID
CP0938691
Compound Name
SID144198206
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Structure
Formula
C30H29F3N4O4
Molecular Weight
566.58
Canonical SMILES
CC(C)NC(=O)N1Cc2cc(C(=O)NCC(F)(F)F)nc(-c3cccc(-c4cc5ccccc5o4)c3)c2[C@H]1CCO
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InChI
InChI=1S/C30H29F3N4O4/c1-17(2)35-29(40)37-15-21-13-22(28(39)34-16-30(31,32)33)36-27(26(21)23(37)10-11-38)20-8-5-7-18(12-20)25-14-19-6-3-4-9-24(19)41-25/h3-9,12-14,17,23,38H,10-11,15-16H2,1-2H3,(H,34,39)(H,35,40)/t23-/m1/s1
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InChIKey
WUGUQQZCGONQFT-HSZRJFAPSA-N
Physicochemical Property
logP
5.811
Rotatable Bonds
7
Heavy Atom Count
41
Polar Areas
107.7
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
5
Complexity
41

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 60192158
ChEMBL ID
CHEMBL2360567
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06124, Paired box protein Pax-8
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000097 RMG-I Homo sapiens (Human)  1
1
AC50 = 7200 nM
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