General Information of the Compound
Compound ID
CP0938690
Compound Name
SID144199873
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Structure
Formula
C39H43N3O3
Molecular Weight
601.791
Canonical SMILES
C[C@H]1CN([C@@H](C)CO)C(=O)c2c(c3ccccc3n2C)-c2ccccc2CO[C@@H]1CN(C)Cc1ccc(-c2ccccc2)cc1
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InChI
InChI=1S/C39H43N3O3/c1-27-22-42(28(2)25-43)39(44)38-37(34-16-10-11-17-35(34)41(38)4)33-15-9-8-14-32(33)26-45-36(27)24-40(3)23-29-18-20-31(21-19-29)30-12-6-5-7-13-30/h5-21,27-28,36,43H,22-26H2,1-4H3/t27-,28-,36+/m0/s1
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InChIKey
LYMUYLCMDRKWKZ-KAUPTSPVSA-N
Physicochemical Property
logP
7.0022
Rotatable Bonds
7
Heavy Atom Count
45
Polar Areas
57.94
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
45

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 60193731
ChEMBL ID
CHEMBL2358805
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06124, Paired box protein Pax-8
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000097 RMG-I Homo sapiens (Human)  1
1
AC50 = 24940 nM
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