General Information of the Compound
Compound ID
CP0936827
Compound Name
(R)-Nomega-(6-Aminohexyl)aminocarbonyl-Nalpha-diphenylacetyl-(4-hydroxy benzyl)argininamide bis(hydrotrifluoroacetate)
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Structure
Formula
C36H46F3N7O6
Molecular Weight
729.801
Canonical SMILES
NCCCCCCNC(=O)/N=C(/N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1.O=C(O)C(F)(F)F
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InChI
InChI=1S/C34H45N7O4.C2HF3O2/c35-21-9-1-2-10-22-38-34(45)41-33(36)37-23-11-16-29(31(43)39-24-25-17-19-28(42)20-18-25)40-32(44)30(26-12-5-3-6-13-26)27-14-7-4-8-15-27;3-2(4,5)1(6)7/h3-8,12-15,17-20,29-30,42H,1-2,9-11,16,21-24,35H2,(H,39,43)(H,40,44)(H4,36,37,38,41,45);(H,6,7)/t29-;/m1./s1
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InChIKey
OXYALBKRGGKVQU-XXIQNXCHSA-N
Physicochemical Property
logP
3.8718
Rotatable Bonds
17
Heavy Atom Count
52
Polar Areas
221.26
Hydrogen Bond Donor Count
8
Hydrogen Bond Acceptor Count
6
Complexity
52

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 73351131
ChEMBL ID
CHEMBL2440934
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02259, Neuropeptide Y receptor type 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  1
1
Ki = 9.9 nM
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