General Information of the Compound
Compound ID
CP0933801
Compound Name
SID131464572
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Structure
Formula
C30H33N3O2
Molecular Weight
467.613
Canonical SMILES
O=C(Cc1cccnc1)N1CCCCN2[C@H](C1)[C@H](c1ccc(/C=C/c3ccccc3)cc1)[C@@H]2CO
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InChI
InChI=1S/C30H33N3O2/c34-22-28-30(26-14-12-24(13-15-26)11-10-23-7-2-1-3-8-23)27-21-32(17-4-5-18-33(27)28)29(35)19-25-9-6-16-31-20-25/h1-3,6-16,20,27-28,30,34H,4-5,17-19,21-22H2/b11-10+/t27-,28+,30+/m1/s1
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InChIKey
PMMZXIZMKPITAD-VWEFUHOQSA-N
Physicochemical Property
logP
4.2458
Rotatable Bonds
6
Heavy Atom Count
35
Polar Areas
56.67
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 54669059
ChEMBL ID
CHEMBL2359037
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06124, Paired box protein Pax-8
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000097 RMG-I Homo sapiens (Human)  1
1
AC50 = 4420 nM
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