General Information of the Compound
Compound ID
CP0930550
Compound Name
SID85805840
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Structure
Formula
C35H41N5O5
Molecular Weight
611.743
Canonical SMILES
Cc1cc(C(=O)Nc2cccc3c2O[C@H](CN(C)Cc2ccc(Oc4ccccc4)cc2)[C@@H](C)CN([C@H](C)CO)C3=O)n(C)n1
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InChI
InChI=1S/C35H41N5O5/c1-23-19-40(25(3)22-41)35(43)29-12-9-13-30(36-34(42)31-18-24(2)37-39(31)5)33(29)45-32(23)21-38(4)20-26-14-16-28(17-15-26)44-27-10-7-6-8-11-27/h6-18,23,25,32,41H,19-22H2,1-5H3,(H,36,42)/t23-,25+,32+/m0/s1
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InChIKey
UFJFLQUSVAOZJI-OQIQTSLJSA-N
Physicochemical Property
logP
5.12522
Rotatable Bonds
10
Heavy Atom Count
45
Polar Areas
109.16
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
8
Complexity
45

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44498882
ChEMBL ID
CHEMBL2354966
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06124, Paired box protein Pax-8
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000097 RMG-I Homo sapiens (Human)  1
1
AC50 = 13220 nM
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