General Information of the Compound
Compound ID
CP0925352
Compound Name
rac-N-Methyl[9-(3-trifluoromethylphenylsulfonyl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl]amine hydrochloride
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Structure
Formula
C20H20ClF3N2O2S
Molecular Weight
444.906
Canonical SMILES
CNC1CCc2c(c3ccccc3n2S(=O)(=O)c2cccc(C(F)(F)F)c2)C1.Cl
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InChI
InChI=1S/C20H19F3N2O2S.ClH/c1-24-14-9-10-19-17(12-14)16-7-2-3-8-18(16)25(19)28(26,27)15-6-4-5-13(11-15)20(21,22)23;/h2-8,11,14,24H,9-10,12H2,1H3;1H
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InChIKey
GRNWLULSBKLATH-UHFFFAOYSA-N
Physicochemical Property
logP
4.3956
Rotatable Bonds
3
Heavy Atom Count
29
Polar Areas
51.1
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
29

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 71451604
SID: 163445982
ChEMBL ID
CHEMBL2165566
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 17.12 nM
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