General Information of the Compound
Compound ID
CP0921628
Compound Name
3-Benzyl-1-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indole oxalic acid
    Show/Hide
Structure
Formula
C23H26N2O4
Molecular Weight
394.471
Canonical SMILES
CN1CCC[C@H]1Cn1cc(Cc2ccccc2)c2ccccc21.O=C(O)C(=O)O
    Show/Hide
InChI
InChI=1S/C21H24N2.C2H2O4/c1-22-13-7-10-19(22)16-23-15-18(14-17-8-3-2-4-9-17)20-11-5-6-12-21(20)23;3-1(4)2(5)6/h2-6,8-9,11-12,15,19H,7,10,13-14,16H2,1H3;(H,3,4)(H,5,6)/t19-;/m0./s1
    Show/Hide
InChIKey
STIGRNOVZGJGCF-FYZYNONXSA-N
Physicochemical Property
logP
3.4819
Rotatable Bonds
4
Heavy Atom Count
29
Polar Areas
82.77
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Complexity
29

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 44397118
ChEMBL ID
CHEMBL433765
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 29 nM
   TI
   LI
   LO
   TS