General Information of the Compound
Compound ID
CP0921487
Compound Name
MOTILIN_065
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Structure
Formula
C26H33FN6O
Molecular Weight
464.589
Canonical SMILES
C[C@@H]1CN(Cc2ccn(-c3cccnc3N3CCC(Oc4ccccc4F)CC3)n2)C[C@H](C)N1
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InChI
InChI=1S/C26H33FN6O/c1-19-16-31(17-20(2)29-19)18-21-9-15-33(30-21)24-7-5-12-28-26(24)32-13-10-22(11-14-32)34-25-8-4-3-6-23(25)27/h3-9,12,15,19-20,22,29H,10-11,13-14,16-18H2,1-2H3/t19-,20+
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InChIKey
UTYHBMHIEFMPCP-BGYRXZFFSA-N
Physicochemical Property
logP
3.6364
Rotatable Bonds
6
Heavy Atom Count
34
Polar Areas
58.45
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 16749781
SID: 26735886
ChEMBL ID
CHEMBL2364327
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01121, Motilin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 6.31 nM
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