General Information of the Compound
Compound ID
CP0919150
Compound Name
1-((R)-9-Amino-4-(2,2-diphenylacetamido)-1-(4-hydroxyphenyl)-3,11,16-trioxo-20,23-dioxa-2,8,10,17-tetraazapentacos-9-en-25-yl)-2,6-dimethyl-4-(3-(1,1,3-trimethyl-1H-benzo[e]indol-2(3H)-ylidene)prop-1-enyl)pyridinium hydrotrifluoroacetate
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Structure
Formula
C66H77F3N8O9
Molecular Weight
1183.383
Canonical SMILES
Cc1cc(/C=C/C=C2\N(C)c3ccc4ccccc4c3C2(C)C)cc(C)[n+]1CCOCCOCCNC(=O)CCCCC(=O)/N=C(/N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1.O=C([O-])C(F)(F)F
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InChI
InChI=1S/C64H76N8O7.C2HF3O2/c1-45-42-48(18-16-26-56-64(3,4)60-53-24-13-12-19-49(53)31-34-55(60)71(56)5)43-46(2)72(45)37-39-79-41-40-78-38-36-66-57(74)27-14-15-28-58(75)70-63(65)67-35-17-25-54(61(76)68-44-47-29-32-52(73)33-30-47)69-62(77)59(50-20-8-6-9-21-50)51-22-10-7-11-23-51;3-2(4,5)1(6)7/h6-13,16,18-24,26,29-34,42-43,54,59H,14-15,17,25,27-28,35-41,44H2,1-5H3,(H6-,65,66,67,68,69,70,73,74,75,76,77);(H,6,7)/t54-;/m1./s1
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InChIKey
YAOYZZOGPQBNJX-KINGROEASA-N
Physicochemical Property
logP
7.62724
Rotatable Bonds
27
Heavy Atom Count
86
Polar Areas
240.72
Hydrogen Bond Donor Count
6
Hydrogen Bond Acceptor Count
10
Complexity
86

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 54583331
ChEMBL ID
CHEMBL1774220
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02259, Neuropeptide Y receptor type 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  1
1
Ki = 130 nM
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   LI
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