General Information of the Compound
Compound ID
CP0919147
Compound Name
1-(6-((Z)-amino((R)-4-(2,2-diphenylacetamido)-5-(4-hydroxybenzylamino)-5-oxopentylamino)methyleneamino)-6-oxohexyl)-4-((E)-2-(1,2,3,5,6,7-hexahydropyrido[3,2,1-ij]quinolin-9-yl)vinyl)-2,6-dimethylpyridinium 2,2,2-trifluoroacetate
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Structure
Formula
C56H64F3N7O6
Molecular Weight
988.165
Canonical SMILES
Cc1cc(/C=C/c2cc3c4c(c2)CCCN4CCC3)cc(C)[n+]1CCCCCC(=O)/N=C(/N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1.O=C([O-])C(F)(F)F
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InChI
InChI=1S/C54H63N7O4.C2HF3O2/c1-38-33-41(23-24-42-35-45-19-13-30-60-31-14-20-46(36-42)51(45)60)34-39(2)61(38)32-11-5-10-22-49(63)59-54(55)56-29-12-21-48(52(64)57-37-40-25-27-47(62)28-26-40)58-53(65)50(43-15-6-3-7-16-43)44-17-8-4-9-18-44;3-2(4,5)1(6)7/h3-4,6-9,15-18,23-28,33-36,48,50H,5,10-14,19-22,29-32,37H2,1-2H3,(H5-,55,56,57,58,59,62,63,64,65);(H,6,7)/t48-;/m1./s1
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InChIKey
QBTZAFQFWAVWCS-AKZQISGYSA-N
Physicochemical Property
logP
6.86914
Rotatable Bonds
19
Heavy Atom Count
72
Polar Areas
193.16
Hydrogen Bond Donor Count
5
Hydrogen Bond Acceptor Count
7
Complexity
72

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 54582342
ChEMBL ID
CHEMBL1774203
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02259, Neuropeptide Y receptor type 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  1
1
Ki = 29 nM
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