General Information of the Compound
Compound ID
CP0919009
Compound Name
1-((R)-9-Amino-4-(2,2-diphenylacetamido)-1-(4-hydroxyphenyl)-3,11-dioxo-2,8,10,12-tetraazahexadec-9-en-16-yl)-4-((E)-2-(1,2,3,5,6,7-hexahydropyrido[3,2,1-ij]quinolin-9-yl)ethenyl)-2,6-dimethylpyridinium-hydrotrifluoroacetate
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Structure
Formula
C55H63F3N8O6
Molecular Weight
989.153
Canonical SMILES
Cc1cc(/C=C/c2cc3c4c(c2)CCCN4CCC3)cc(C)[n+]1CCCCNC(=O)/N=C(/N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1.O=C([O-])C(F)(F)F
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InChI
InChI=1S/C53H62N8O4.C2HF3O2/c1-37-32-40(21-22-41-34-44-18-12-29-60-30-13-19-45(35-41)49(44)60)33-38(2)61(37)31-10-9-27-56-53(65)59-52(54)55-28-11-20-47(50(63)57-36-39-23-25-46(62)26-24-39)58-51(64)48(42-14-5-3-6-15-42)43-16-7-4-8-17-43;3-2(4,5)1(6)7/h3-8,14-17,21-26,32-35,47-48H,9-13,18-20,27-31,36H2,1-2H3,(H6-,54,55,56,57,58,59,62,63,64,65);(H,6,7)/t47-;/m1./s1
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InChIKey
XDPWIHSMYHOLPY-QBGRQLKXSA-N
Physicochemical Property
logP
6.27194
Rotatable Bonds
18
Heavy Atom Count
72
Polar Areas
205.19
Hydrogen Bond Donor Count
6
Hydrogen Bond Acceptor Count
7
Complexity
72

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 54587222
ChEMBL ID
CHEMBL1774215
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02259, Neuropeptide Y receptor type 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  1
1
Ki = 140 nM
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