General Information of the Compound
Compound ID
CP0917676
Compound Name
rac-N-Methyl[6-methoxy-9-(3-trifluoromethylphenylsulfonyl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl]amine hydrochloride
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Structure
Formula
C21H22ClF3N2O3S
Molecular Weight
474.932
Canonical SMILES
CNC1CCc2c(c3cc(OC)ccc3n2S(=O)(=O)c2cccc(C(F)(F)F)c2)C1.Cl
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InChI
InChI=1S/C21H21F3N2O3S.ClH/c1-25-14-6-8-19-17(11-14)18-12-15(29-2)7-9-20(18)26(19)30(27,28)16-5-3-4-13(10-16)21(22,23)24;/h3-5,7,9-10,12,14,25H,6,8,11H2,1-2H3;1H
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InChIKey
IHEFGTLEIXEYCG-UHFFFAOYSA-N
Physicochemical Property
logP
4.4042
Rotatable Bonds
4
Heavy Atom Count
31
Polar Areas
60.33
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 71449797
SID: 163445983
ChEMBL ID
CHEMBL2165567
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 13.1 nM
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