General Information of the Compound
Compound ID
CP0915300
Compound Name
SID131409441
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Structure
Formula
C38H42N4O6
Molecular Weight
650.776
Canonical SMILES
C[C@H]1CN([C@@H](C)CO)C(=O)Cc2cc(NC(=O)Nc3ccc4c(c3)OCO4)ccc2O[C@@H]1CN(C)Cc1ccc(-c2ccccc2)cc1
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InChI
InChI=1S/C38H42N4O6/c1-25-20-42(26(2)23-43)37(44)18-30-17-31(39-38(45)40-32-14-16-34-35(19-32)47-24-46-34)13-15-33(30)48-36(25)22-41(3)21-27-9-11-29(12-10-27)28-7-5-4-6-8-28/h4-17,19,25-26,36,43H,18,20-24H2,1-3H3,(H2,39,40,45)/t25-,26-,36+/m0/s1
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InChIKey
AIDUNWUCHWLKPO-BBUMLKAKSA-N
Physicochemical Property
logP
6.0073
Rotatable Bonds
9
Heavy Atom Count
48
Polar Areas
112.6
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
7
Complexity
48

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 54614461
ChEMBL ID
CHEMBL2355487
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06124, Paired box protein Pax-8
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000097 RMG-I Homo sapiens (Human)  1
1
AC50 = 5450 nM
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