General Information of the Compound
Compound ID
CP0914643
Compound Name
3-(1-oxo-5-(((R)-1-(4-(piperidin-1-yl)benzyl)piperidin-2-yl)methoxy)isoindolin-2-yl)piperidine-2,6-dione
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Structure
Formula
C31H38N4O4
Molecular Weight
530.669
Canonical SMILES
O=C1CCC(N2Cc3cc(OC[C@H]4CCCCN4Cc4ccc(N5CCCCC5)cc4)ccc3C2=O)C(=O)N1
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InChI
InChI=1S/C31H38N4O4/c36-29-14-13-28(30(37)32-29)35-20-23-18-26(11-12-27(23)31(35)38)39-21-25-6-2-5-17-34(25)19-22-7-9-24(10-8-22)33-15-3-1-4-16-33/h7-12,18,25,28H,1-6,13-17,19-21H2,(H,32,36,37)/t25-,28?/m1/s1
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InChIKey
YMHQRQIVWNGUMS-RXVAYIKUSA-N
Physicochemical Property
logP
3.8714
Rotatable Bonds
7
Heavy Atom Count
39
Polar Areas
82.19
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
39

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 156500702
ChEMBL ID
CHEMBL4848069
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT07282, Protein Wiz
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
AC50 = 0.37 nM
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