General Information of the Compound
Compound ID
CP0908125
Compound Name
SID85797536
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Structure
Formula
C36H52N4O6
Molecular Weight
636.834
Canonical SMILES
C[C@@H]1CCCCO[C@H](CN(C)C(=O)C2CCCCC2)[C@@H](C)CN([C@@H](C)CO)C(=O)c2cc(NC(=O)Nc3ccccc3)ccc2O1
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InChI
InChI=1S/C36H52N4O6/c1-25-22-40(26(2)24-41)35(43)31-21-30(38-36(44)37-29-16-9-6-10-17-29)18-19-32(31)46-27(3)13-11-12-20-45-33(25)23-39(4)34(42)28-14-7-5-8-15-28/h6,9-10,16-19,21,25-28,33,41H,5,7-8,11-15,20,22-24H2,1-4H3,(H2,37,38,44)/t25-,26-,27+,33+/m0/s1
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InChIKey
JXPVOOMRKPVBDG-SQQWPVGBSA-N
Physicochemical Property
logP
6.1648
Rotatable Bonds
7
Heavy Atom Count
46
Polar Areas
120.44
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
6
Complexity
46

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44490910
ChEMBL ID
CHEMBL2362006
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06124, Paired box protein Pax-8
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000097 RMG-I Homo sapiens (Human)  1
1
AC50 = 5390 nM
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