General Information of the Compound
Compound ID
CP0908124
Compound Name
SID144194869
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Structure
Formula
C26H25FN2O3
Molecular Weight
432.495
Canonical SMILES
O=C(C1CCC1)N1CC(=O)N2[C@H](C1)[C@H](c1ccc(C#Cc3cccc(F)c3)cc1)[C@@H]2CO
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InChI
InChI=1S/C26H25FN2O3/c27-21-6-1-3-18(13-21)8-7-17-9-11-19(12-10-17)25-22-14-28(26(32)20-4-2-5-20)15-24(31)29(22)23(25)16-30/h1,3,6,9-13,20,22-23,25,30H,2,4-5,14-16H2/t22-,23+,25+/m1/s1
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InChIKey
PNTOBEGYTHNSOZ-CUYJMHBOSA-N
Physicochemical Property
logP
2.5231
Rotatable Bonds
3
Heavy Atom Count
32
Polar Areas
60.85
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 60188862
ChEMBL ID
CHEMBL2361832
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06124, Paired box protein Pax-8
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000097 RMG-I Homo sapiens (Human)  1
1
AC50 = 10630 nM
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