General Information of the Compound
Compound ID
CP0894863
Compound Name
1-(4-Isopropylbenzenesulfonyl)-5-methoxy-3-(4-methyl-[1,4]-diazepan-1-ylmethyl)-1H-indole Dihydrochloride
    Show/Hide
Structure
Formula
C25H35Cl2N3O3S
Molecular Weight
528.546
Canonical SMILES
COc1ccc2c(c1)c(CN1CCCN(C)CC1)cn2S(=O)(=O)c1ccc(C(C)C)cc1.Cl.Cl
    Show/Hide
InChI
InChI=1S/C25H33N3O3S.2ClH/c1-19(2)20-6-9-23(10-7-20)32(29,30)28-18-21(17-27-13-5-12-26(3)14-15-27)24-16-22(31-4)8-11-25(24)28;;/h6-11,16,18-19H,5,12-15,17H2,1-4H3;2*1H
    Show/Hide
InChIKey
ZOVHVSOYAFHSFK-UHFFFAOYSA-N
Physicochemical Property
logP
4.9914
Rotatable Bonds
6
Heavy Atom Count
34
Polar Areas
54.78
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
6
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 137658916
ChEMBL ID
CHEMBL4101284
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 2 nM
   TI
   LI
   LO
   TS