General Information of the Compound
Compound ID
CP0891360
Compound Name
SID87541097
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Structure
Formula
C34H44F6N4O6
Molecular Weight
718.736
Canonical SMILES
C[C@H]1CCCCO[C@H](CN(C)C(=O)Nc2ccc(C(F)(F)F)cc2)[C@@H](C)CN([C@@H](C)CO)C(=O)c2cc(NC(=O)CCC(F)(F)F)ccc2O1
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InChI
InChI=1S/C34H44F6N4O6/c1-21-18-44(22(2)20-45)31(47)27-17-26(41-30(46)14-15-33(35,36)37)12-13-28(27)50-23(3)7-5-6-16-49-29(21)19-43(4)32(48)42-25-10-8-24(9-11-25)34(38,39)40/h8-13,17,21-23,29,45H,5-7,14-16,18-20H2,1-4H3,(H,41,46)(H,42,48)/t21-,22-,23-,29+/m0/s1
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InChIKey
VJUSOOVXAHQYTN-FSDPBTBWSA-N
Physicochemical Property
logP
6.9458
Rotatable Bonds
8
Heavy Atom Count
50
Polar Areas
120.44
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
6
Complexity
50

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44617893
ChEMBL ID
CHEMBL2354501
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06124, Paired box protein Pax-8
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000097 RMG-I Homo sapiens (Human)  1
1
AC50 = 6570 nM
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