General Information of the Compound
Compound ID
CP0888888
Compound Name
SID87540146
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Structure
Formula
C34H40F3N3O4
Molecular Weight
611.705
Canonical SMILES
C[C@@H]1CN([C@@H](C)CO)C(=O)Cc2cc(NC(=O)CCC(F)(F)F)ccc2O[C@H]1CN(C)Cc1ccc(-c2ccccc2)cc1
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InChI
InChI=1S/C34H40F3N3O4/c1-23-19-40(24(2)22-41)33(43)18-28-17-29(38-32(42)15-16-34(35,36)37)13-14-30(28)44-31(23)21-39(3)20-25-9-11-27(12-10-25)26-7-5-4-6-8-26/h4-14,17,23-24,31,41H,15-16,18-22H2,1-3H3,(H,38,42)/t23-,24+,31+/m1/s1
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InChIKey
DFSBUGSUDBGGAL-OXYPMYLPSA-N
Physicochemical Property
logP
5.9156
Rotatable Bonds
10
Heavy Atom Count
44
Polar Areas
82.11
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
44

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44616945
ChEMBL ID
CHEMBL2357009
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06124, Paired box protein Pax-8
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000097 RMG-I Homo sapiens (Human)  1
1
AC50 = 8610 nM
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