General Information of the Compound
Compound ID
CP0877506
Compound Name
N-[3-(4,5-dihydro-1H-imidazol-2-ylhydrazono-2,3-dihydro-1H-inden-5-yl)-4-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-sulfonamide
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Structure
Formula
C21H24N6O3S
Molecular Weight
440.529
Canonical SMILES
CN1CCOc2ccc(S(=O)(=O)Nc3ccc4c(c3)/C(=N\NC3=NCCN3)CC4)cc21
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InChI
InChI=1S/C21H24N6O3S/c1-27-10-11-30-20-7-5-16(13-19(20)27)31(28,29)26-15-4-2-14-3-6-18(17(14)12-15)24-25-21-22-8-9-23-21/h2,4-5,7,12-13,26H,3,6,8-11H2,1H3,(H2,22,23,25)/b24-18-
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InChIKey
LPULTYDZZMPHIN-MOHJPFBDSA-N
Physicochemical Property
logP
1.5151
Rotatable Bonds
4
Heavy Atom Count
31
Polar Areas
107.42
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
8
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45483628
ChEMBL ID
CHEMBL576967
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 70 nM
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