General Information of the Compound
Compound ID
CP0869609
Compound Name
3-(2-(2-(benzyloxy)-5-chlorophenyl)-5-chloro-1H-pyrrol-1-yl)benzoic acid
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Structure
Formula
C24H17Cl2NO3
Molecular Weight
438.31
Canonical SMILES
O=C(O)c1cccc(-n2c(Cl)ccc2-c2cc(Cl)ccc2OCc2ccccc2)c1
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InChI
InChI=1S/C24H17Cl2NO3/c25-18-9-11-22(30-15-16-5-2-1-3-6-16)20(14-18)21-10-12-23(26)27(21)19-8-4-7-17(13-19)24(28)29/h1-14H,15H2,(H,28,29)
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InChIKey
NPRLFJODKAZGAY-UHFFFAOYSA-N
Physicochemical Property
logP
6.7283
Rotatable Bonds
6
Heavy Atom Count
30
Polar Areas
51.46
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44413078
ChEMBL ID
CHEMBL377338
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01205, Prostaglandin E2 receptor EP1 subtype
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 25.12 nM
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