General Information of the Compound
Compound ID
CP0867895
Compound Name
endo-2-(8-(bis(2-chlorophenyl)methyl)-3-(4-hydroxybenzyl)-8-azabicyclo[3.2.1]octan-3-yl)acetamide
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Formula
C29H30Cl2N2O2
Molecular Weight
509.477
Canonical SMILES
NC(=O)C[C@]1(Cc2ccc(O)cc2)C[C@H]2CC[C@@H](C1)N2C(c1ccccc1Cl)c1ccccc1Cl
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InChI
InChI=1S/C29H30Cl2N2O2/c30-25-7-3-1-5-23(25)28(24-6-2-4-8-26(24)31)33-20-11-12-21(33)17-29(16-20,18-27(32)35)15-19-9-13-22(34)14-10-19/h1-10,13-14,20-21,28,34H,11-12,15-18H2,(H2,32,35)/t20-,21+,29-
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InChIKey
UYDBENOANLFGKT-VPIZKCOQSA-N
Physicochemical Property
logP
6.5197
Rotatable Bonds
7
Heavy Atom Count
35
Polar Areas
66.56
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL3084556
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 17 nM
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