General Information of the Compound
Compound ID
CP0865183
Compound Name
[800CW]Adam GPI Monomer
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Structure
Formula
C81H104N5Na4O26PS4
Molecular Weight
1814.934
Canonical SMILES
CC1(C)C(/C=C/C2=C(Oc3ccc(S(=O)(=O)[O-])cc3)/C(=C/C=C3/N(CCCCS(=O)(=O)[O-])c4ccc(S(=O)(=O)[O-])cc4C3(C)C)CCC2)=[N+](CCCCCC(=O)NCCCCCC(=O)NC23CC4(CCC=O)CC(CCC=O)(CC(CCC(=O)N[C@@H](CCP(=O)(O)CC(CCC(=O)[O-])C(=O)O)C(=O)O)(C4)C2)C3)c2ccc(S(=O)(=O)[O-])cc21.[Na+].[Na+].[Na+].[Na+]
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InChI
InChI=1S/C81H108N5O26PS4.4Na/c1-76(2)62-46-60(116(106,107)108)27-29-65(62)85(67(76)31-20-55-16-13-17-56(73(55)112-58-23-25-59(26-24-58)115(103,104)105)21-32-68-77(3,4)63-47-61(117(109,110)111)28-30-66(63)86(68)41-11-12-45-114(100,101)102)40-10-6-8-18-69(89)82-39-9-5-7-19-71(91)84-81-52-78(36-14-42-87)49-79(53-81,37-15-43-88)51-80(50-78,54-81)38-34-70(90)83-64(75(96)97)35-44-113(98,99)48-57(74(94)95)22-33-72(92)93;;;;/h20-21,23-32,42-43,46-47,57,64H,5-19,22,33-41,44-45,48-54H2,1-4H3,(H10-,82,83,84,89,90,91,92,93,94,95,96,97,98,99,100,101,102,103,104,105,106,107,108,109,110,111);;;;/q;4*+1/p-4/t57?,64-,78?,79?,80?,81?;;;;/m0..../s1
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InChIKey
AEGCHBYDTAPSAE-SZOGVEBJSA-J
Physicochemical Property
logP
-3.5704
Rotatable Bonds
46
Heavy Atom Count
121
Polar Areas
517.75
Hydrogen Bond Donor Count
6
Hydrogen Bond Acceptor Count
24
Complexity
121

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 70693187
ChEMBL ID
CHEMBL2079722
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02647, Glutamate carboxypeptidase 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000141 LNCaP Homo sapiens (Human)  1
1
Kd = 5.4 nM
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