General Information of the Compound
Compound ID
CP0864701
Compound Name
SID87540866
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Structure
Formula
C37H49N3O8S
Molecular Weight
695.879
Canonical SMILES
Cc1ccc(S(=O)(=O)Nc2ccc3c(c2)C(=O)N([C@H](C)CO)C[C@@H](C)[C@@H](CN(C)Cc2ccc4c(c2)OCO4)OCCCC[C@@H](C)O3)cc1
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InChI
InChI=1S/C37H49N3O8S/c1-25-9-13-31(14-10-25)49(43,44)38-30-12-16-33-32(19-30)37(42)40(27(3)23-41)20-26(2)36(45-17-7-6-8-28(4)48-33)22-39(5)21-29-11-15-34-35(18-29)47-24-46-34/h9-16,18-19,26-28,36,38,41H,6-8,17,20-24H2,1-5H3/t26-,27-,28-,36-/m1/s1
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InChIKey
AXBDLHZRWNTTPP-IEPUYCOHSA-N
Physicochemical Property
logP
5.45202
Rotatable Bonds
9
Heavy Atom Count
49
Polar Areas
126.87
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
9
Complexity
49

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44617662
ChEMBL ID
CHEMBL2357149
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06124, Paired box protein Pax-8
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000097 RMG-I Homo sapiens (Human)  1
1
AC50 = 20980 nM
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