General Information of the Compound
| Compound ID |
CP0864258
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| Compound Name |
N-(4-((6,7-Dimethoxyquinazolin-4-yl)oxy)phenyl)-2-(3-isopropyl-1H-pyrazol-5-yl)acetamide
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| Structure |
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| Formula |
C24H25N5O4
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| Molecular Weight |
447.495
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| Canonical SMILES |
COc1cc2ncnc(Oc3ccc(NC(=O)Cc4cc(C(C)C)n[nH]4)cc3)c2cc1OC
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| InChI |
InChI=1S/C24H25N5O4/c1-14(2)19-9-16(28-29-19)10-23(30)27-15-5-7-17(8-6-15)33-24-18-11-21(31-3)22(32-4)12-20(18)25-13-26-24/h5-9,11-14H,10H2,1-4H3,(H,27,30)(H,28,29)
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| InChIKey |
PBQYEUUFZBCPBN-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound