General Information of the Compound
Compound ID
CP0856367
Compound Name
(6aR)-O10-(3-(6-((Tert-butoxycarbonyl)amino)hexanamido)-propyl)apomorphine
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Structure
Formula
C31H43N3O5
Molecular Weight
537.701
Canonical SMILES
CN1CCc2cccc3c2[C@H]1Cc1ccc(OCCCNC(=O)CCCCCNC(=O)OC(C)(C)C)c(O)c1-3
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InChI
InChI=1S/C31H43N3O5/c1-31(2,3)39-30(37)33-16-7-5-6-12-26(35)32-17-9-19-38-25-14-13-22-20-24-27-21(15-18-34(24)4)10-8-11-23(27)28(22)29(25)36/h8,10-11,13-14,24,36H,5-7,9,12,15-20H2,1-4H3,(H,32,35)(H,33,37)/t24-/m1/s1
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InChIKey
QYSHFCPJVHYHPL-XMMPIXPASA-N
Physicochemical Property
logP
5.1145
Rotatable Bonds
11
Heavy Atom Count
39
Polar Areas
100.13
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
6
Complexity
39

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 76311289
ChEMBL ID
CHEMBL3134063
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000386 Flp-In-CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 266 nM
   TI
   LI
   LO
   TS
2
IC50 = 6540 nM
   TI
   LI
   LO
   TS