General Information of the Compound
Compound ID
CP0853768
Compound Name
N-(9-Methyl-9H-carbazol-3-yl)-2-[4-(2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-piperidin-1-yl]-acetamide
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Structure
Formula
C28H29ClN4O3
Molecular Weight
505.018
Canonical SMILES
Cl.Cn1c2ccccc2c2cc(NC(=O)CN3CCC(N4C(=O)OCc5ccccc54)CC3)ccc21
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InChI
InChI=1S/C28H28N4O3.ClH/c1-30-25-9-5-3-7-22(25)23-16-20(10-11-26(23)30)29-27(33)17-31-14-12-21(13-15-31)32-24-8-4-2-6-19(24)18-35-28(32)34;/h2-11,16,21H,12-15,17-18H2,1H3,(H,29,33);1H
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InChIKey
TXMICMPUWWUREW-UHFFFAOYSA-N
Physicochemical Property
logP
5.313
Rotatable Bonds
4
Heavy Atom Count
36
Polar Areas
66.81
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 9983623
SID: 14961659
ChEMBL ID
CHEMBL557540
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01653, Neuropeptide Y receptor type 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000049 C6 Rattus norvegicus (Rat)  1
1
IC50 = 9.6 nM
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