General Information of the Compound
Compound ID
CP0851387
Compound Name
(+)2-Fluorophenylmethyl-3-(2-chlorospiro[4,5-dihydrothieno[2,3-c]-pyran-7,4'-piperidine]-1'-yl)-N,N-dimethylpropanamide L-tatrtaric acid salt
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Structure
Formula
C27H34ClFN2O8S
Molecular Weight
601.093
Canonical SMILES
CN(C)C(=O)C(Cc1ccccc1F)CN1CCC2(CC1)OCCc1cc(Cl)sc12.O=C(O)C(O)C(O)C(=O)O
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InChI
InChI=1S/C23H28ClFN2O2S.C4H6O6/c1-26(2)22(28)18(13-16-5-3-4-6-19(16)25)15-27-10-8-23(9-11-27)21-17(7-12-29-23)14-20(24)30-21;5-1(3(7)8)2(6)4(9)10/h3-6,14,18H,7-13,15H2,1-2H3;1-2,5-6H,(H,7,8)(H,9,10)
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InChIKey
IAJRQPVDELSPGT-UHFFFAOYSA-N
Physicochemical Property
logP
2.2289
Rotatable Bonds
8
Heavy Atom Count
40
Polar Areas
147.84
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
8
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 70691174
ChEMBL ID
CHEMBL2088055
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01200, Delta-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 400 nM
   TI
   LI
   LO
   TS
Protein ID: PT00983, Kappa-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 400 nM
   TI
   LI
   LO
   TS
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 400 nM
   TI
   LI
   LO
   TS
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 0.0892 nM
   TI
   LI
   LO
   TS