General Information of the Compound
Compound ID
CP0850584
Compound Name
Spiroxatrine oxalate
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Structure
Formula
C24H27N3O7
Molecular Weight
469.494
Canonical SMILES
O=C(O)C(=O)O.O=C1NCN(c2ccccc2)C12CCN(CC1COc3ccccc3O1)CC2
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InChI
InChI=1S/C22H25N3O3.C2H2O4/c26-21-22(25(16-23-21)17-6-2-1-3-7-17)10-12-24(13-11-22)14-18-15-27-19-8-4-5-9-20(19)28-18;3-1(4)2(5)6/h1-9,18H,10-16H2,(H,23,26);(H,3,4)(H,5,6)
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InChIKey
BCXYKBJATNURNF-UHFFFAOYSA-N
Physicochemical Property
logP
1.4105
Rotatable Bonds
3
Heavy Atom Count
34
Polar Areas
128.64
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
7
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 122179567
ChEMBL ID
CHEMBL3585387
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 323.59 nM
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