General Information of the Compound
Compound ID
CP0845119
Compound Name
1-((R)-9-Amino-4-(2,2-diphenylacetamido)-1-(4-hydroxyphenyl)-3,11,15-trioxo-19,22-dioxa-2,8,10,16-tetraazatetracos-9-en-24-yl)-2,6-dimethyl-4-(3-(1,1,3-trimethyl-1H-benzo[e]indol-2(3H)-ylidene)prop-1-enyl)pyridinium hydrotrifluoroacetate
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Structure
Formula
C65H75F3N8O9
Molecular Weight
1169.356
Canonical SMILES
Cc1cc(/C=C/C=C2\N(C)c3ccc4ccccc4c3C2(C)C)cc(C)[n+]1CCOCCOCCNC(=O)CCCC(=O)/N=C(/N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1.O=C([O-])C(F)(F)F
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InChI
InChI=1S/C63H74N8O7.C2HF3O2/c1-44-41-47(17-14-25-55-63(3,4)59-52-23-13-12-18-48(52)30-33-54(59)70(55)5)42-45(2)71(44)36-38-78-40-39-77-37-35-65-56(73)26-15-27-57(74)69-62(64)66-34-16-24-53(60(75)67-43-46-28-31-51(72)32-29-46)68-61(76)58(49-19-8-6-9-20-49)50-21-10-7-11-22-50;3-2(4,5)1(6)7/h6-14,17-23,25,28-33,41-42,53,58H,15-16,24,26-27,34-40,43H2,1-5H3,(H6-,64,65,66,67,68,69,72,73,74,75,76);(H,6,7)/t53-;/m1./s1
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InChIKey
YSIHTZJKUBINMD-JFZWEQCNSA-N
Physicochemical Property
logP
7.23714
Rotatable Bonds
26
Heavy Atom Count
85
Polar Areas
240.72
Hydrogen Bond Donor Count
6
Hydrogen Bond Acceptor Count
10
Complexity
85

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 54582349
ChEMBL ID
CHEMBL1774219
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02259, Neuropeptide Y receptor type 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  1
1
Ki = 96 nM
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